{"id":"W3184579517","doi":"10.1371/journal.ppat.1009682","title":"Development of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration","year":2021,"lang":"en","type":"review","venue":"PLoS Pathogens","topic":"Parasitic Diseases Research and Treatment","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Bayer; Bill and Melinda Gates Foundation","keywords":"Onchocerciasis; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009682065,0.0003607377,0.0004281319,0.0008844244,0.0001924547,0.0008058382,0.0003993612,0.0006446037,0.003123457],"category_scores_gemma":[0.000408808,0.0001527303,0.0004454477,0.0003504383,0.0002810013,0.0008767687,0.0006103287,0.001831296,0.001080921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004015459,"about_ca_system_score_gemma":0.0006079354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005064319,"about_ca_topic_score_gemma":0.001061615,"domain_scores_codex":[0.9997417,0.00006719401,0.00001788316,0.00003803184,0.00009862348,0.0000364387],"domain_scores_gemma":[0.9997488,0.00003581984,0.00003543259,0.00001167475,0.00009940974,0.00006895887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007905189,0.00154043,0.001076466,0.002306293,0.0001510963,0.0007922159,0.0002303844,0.001047885,0.1980465,0.01137473,0.02099215,0.7616513],"study_design_scores_gemma":[0.0006302302,0.009301076,0.00751617,0.001214348,0.0003408786,0.002468521,0.000167181,0.002061061,0.1164628,0.003741574,0.8560125,0.00008374381],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.256332,0.602309,0.03633397,0.02216706,0.003187997,0.001085535,0.001369836,0.0008118184,0.07640272],"genre_scores_gemma":[0.4694747,0.4385236,0.04448314,0.01286413,0.001253248,0.0003354372,0.002226019,0.0001495221,0.03069016],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003123457,"threshold_uncertainty_score":0.01044899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.211447471092209,"score_gpt":0.4521781374696034,"score_spread":0.2407306663773944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}