{"id":"W3184603486","doi":"10.1139/bcb-2020-0267","title":"Dexmedetomidine upregulates the expression of miR-493-5p, inhibiting growth and inducing the apoptosis of lung adenocarcinoma cells by targeting RASL11B","year":2021,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"microRNA; Dexmedetomidine; Adenocarcinoma; Apoptosis; Downregulation and upregulation; Cancer research; Lung cancer; Biology; A549 cell; Cell growth; Cell biology; Cancer; Gene; Medicine; Oncology; Pharmacology; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000892572,0.0001776562,0.0002190848,0.0001769546,0.0001303665,0.0002096541,0.00009480453,0.0001588942,0.0009513447],"category_scores_gemma":[0.0001327488,0.0000800254,0.0002344533,0.00009268405,0.0001385068,0.0001098158,0.0001282836,0.0004282929,0.0002034636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002427387,"about_ca_system_score_gemma":0.0001973014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007512248,"about_ca_topic_score_gemma":0.0009631568,"domain_scores_codex":[0.999899,0.00001609652,0.00001382041,0.00002000139,0.00003182474,0.0000192172],"domain_scores_gemma":[0.9999365,0.00001633136,0.00001815642,0.000005916552,0.000008762329,0.00001439081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004090643,0.00005044333,0.0007122529,0.00004090607,0.000006243934,0.00007067006,0.00001565982,0.00005572417,0.9958515,0.00003659217,0.00007766074,0.00267316],"study_design_scores_gemma":[0.00002070293,0.000422919,0.01069656,0.000004778465,0.0000146281,0.0002068212,0.00003098027,0.0009925136,0.9847502,0.00002661782,0.002828926,0.000004353892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925804,0.002707633,0.002215154,0.0001731518,0.00007284456,0.00003207431,0.0005929576,0.0001188931,0.001506874],"genre_scores_gemma":[0.9952511,0.0008014859,0.002158647,0.0001056001,0.00001096559,0.00003839875,0.0005332076,0.00001152581,0.00108918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009513447,"threshold_uncertainty_score":0.00318259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004202076784322344,"score_gpt":0.2010773382086295,"score_spread":0.1968752614243071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}