{"id":"W3184639007","doi":"10.1016/j.isci.2021.102909","title":"Vascepa protects against high-fat diet-induced glucose intolerance, insulin resistance, and impaired β-cell function","year":2021,"lang":"en","type":"article","venue":"iScience","topic":"Diet and metabolism studies","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Canada Research Chairs; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences","keywords":"Insulin resistance; Eicosapentaenoic acid; Hypertriglyceridemia; Internal medicine; Endocrinology; Docosahexaenoic acid; Type 2 diabetes; Glucose homeostasis; Insulin; Chemistry; Medicine; Diabetes mellitus; Fatty acid; Triglyceride; Biochemistry; Polyunsaturated fatty acid; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001418392,0.0004813585,0.0004591439,0.0005928332,0.0001812578,0.0003211753,0.0002411923,0.0003590042,0.001735278],"category_scores_gemma":[0.0001054861,0.0001822015,0.000356734,0.0002066826,0.0002072514,0.0001972247,0.0001520482,0.001080067,0.0002407602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001588119,"about_ca_system_score_gemma":0.0002279709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006608832,"about_ca_topic_score_gemma":0.0009988025,"domain_scores_codex":[0.9999087,0.00001496995,0.000008054157,0.00001481711,0.00002084818,0.00003251619],"domain_scores_gemma":[0.9998416,0.000009855298,0.00004115839,0.00001425063,0.00001516958,0.00007805069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008634737,0.0008075962,0.0008577739,0.0002024351,0.00007123447,0.00009998446,0.00002036211,0.00008578034,0.97816,0.0001154118,0.0002793804,0.01066529],"study_design_scores_gemma":[0.001579897,0.02445276,0.05712202,0.00009696728,0.0004653644,0.0005739845,0.0001689984,0.0009366694,0.9078327,0.0002022183,0.006534001,0.00003439971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937608,0.003358737,0.0003991319,0.0001492013,0.00008126501,0.00002520506,0.0005718691,0.0001443824,0.001509517],"genre_scores_gemma":[0.9921023,0.003217782,0.0007468499,0.0001987135,0.00004284541,0.00004402632,0.000828798,0.00002774733,0.002790904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001735278,"threshold_uncertainty_score":0.005805075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01527719399552934,"score_gpt":0.2395279462097399,"score_spread":0.2242507522142105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}