{"id":"W3184716687","doi":"10.3389/fcell.2021.708431","title":"Communication Between Autophagy and Insulin Action: At the Crux of Insulin Action-Insulin Resistance?","year":2021,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Insulin resistance; Insulin; Anabolism; Crosstalk; Adipose tissue; Biology; Endocrinology; Internal medicine; Cell biology; Medicine; Apoptosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003478392,0.0005845298,0.001135154,0.001376057,0.0002585267,0.001155537,0.0006578257,0.001024081,0.003306776],"category_scores_gemma":[0.0003818892,0.0001679295,0.0003292632,0.001643333,0.0005150484,0.001724397,0.0007547396,0.001708991,0.002134945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005798921,"about_ca_system_score_gemma":0.0008862351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004599506,"about_ca_topic_score_gemma":0.001009249,"domain_scores_codex":[0.9998746,0.00002559997,0.00001470343,0.00002212655,0.00004696943,0.00001602283],"domain_scores_gemma":[0.9998759,0.00005145976,0.00001573715,0.000005689825,0.00003140852,0.00001973786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008481205,0.00004626979,0.000137067,0.01243026,0.00007678428,0.0003021036,0.0001051404,0.0002377331,0.00317717,0.01101617,0.04430595,0.9280805],"study_design_scores_gemma":[0.0000094263,0.00006120427,0.0005684783,0.002604686,0.00004975188,0.001298777,0.00008959943,0.00004815427,0.0003465801,0.004940785,0.9899697,0.00001293517],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000934793,0.9979808,0.0001274054,0.0004724086,0.000261729,0.000001751641,0.00001256757,0.000009037252,0.001040815],"genre_scores_gemma":[0.0007057,0.9978616,0.0001492458,0.00030579,0.0002439659,0.000003682953,0.0000229019,0.000001911801,0.0007051722],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003306776,"threshold_uncertainty_score":0.01106226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04783213552133676,"score_gpt":0.3312101601287619,"score_spread":0.2833780246074252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}