{"id":"W3184783543","doi":"10.3390/metabo11080476","title":"Untargeted Metabolomics Uncovers the Essential Lysine Transporter in Toxoplasma gondii","year":2021,"lang":"en","type":"article","venue":"Metabolites","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Institute of Genetics and Genomics of Geneva","keywords":"Metabolome; Metabolomics; Biology; Biochemistry; Toxoplasma gondii; Major facilitator superfamily; Metabolite; Transporter; Amino acid; Genetics; Bioinformatics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000168961,0.0003698372,0.0004713933,0.0002227551,0.0001437026,0.0003689746,0.0002203806,0.0003647634,0.000513363],"category_scores_gemma":[0.0001817939,0.0001701527,0.0003648959,0.0002668877,0.0002308261,0.0002261716,0.0002915421,0.0005239212,0.0002858063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002437436,"about_ca_system_score_gemma":0.0001767859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006282958,"about_ca_topic_score_gemma":0.001262891,"domain_scores_codex":[0.9998558,0.00001232823,0.00001362587,0.00004322941,0.00005463083,0.00002049524],"domain_scores_gemma":[0.9998716,0.00002690774,0.00003609812,0.00001611255,0.00002528681,0.00002394356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000102073,0.000006342145,0.0004119035,0.00003921014,0.0000087404,0.00003875887,0.000007453429,0.00003952287,0.9986293,0.00002338829,0.0000303104,0.0006631563],"study_design_scores_gemma":[0.00002595731,0.0002910414,0.03018663,0.00001618491,0.00007542918,0.000597376,0.00006812145,0.003081593,0.9614054,0.0001824614,0.004051009,0.00001887721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878978,0.0017482,0.005197424,0.0002505448,0.00005246294,0.00002320269,0.004031589,0.0001434764,0.0006553657],"genre_scores_gemma":[0.9756833,0.00197388,0.01040871,0.000285031,0.00002115188,0.00004328276,0.009358741,0.0001330709,0.002092776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006282958,"threshold_uncertainty_score":0.00176847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009271292545373802,"score_gpt":0.2438440822629258,"score_spread":0.234572789717552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}