{"id":"W3184783543","doi":"10.3390/metabo11080476","title":"Untargeted Metabolomics Uncovers the Essential Lysine Transporter in Toxoplasma gondii","year":2021,"lang":"en","type":"article","venue":"Metabolites","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Institute of Genetics and Genomics of Geneva","keywords":"Metabolome; Metabolomics; Biology; Biochemistry; Toxoplasma gondii; Major facilitator superfamily; Metabolite; Transporter; Amino acid; Genetics; Bioinformatics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005245787,0.0002906361,0.0005978255,0.0001782734,0.0002417678,0.00004364983,0.0003691581,0.0002036317,0.001583815],"category_scores_gemma":[0.0003689998,0.0002011497,0.0002316797,0.0007714945,0.0004362757,0.0001637476,0.0001571996,0.0006085751,0.0004075248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004137002,"about_ca_system_score_gemma":0.0002127693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001994597,"about_ca_topic_score_gemma":0.0009397601,"domain_scores_codex":[0.9976536,0.0005482559,0.0004645933,0.0004894732,0.0001074365,0.000736642],"domain_scores_gemma":[0.998772,0.0004421013,0.00008917795,0.0005081827,0.000155812,0.00003279013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003005229,0.0003675557,0.05138006,0.00003792478,0.001216161,0.0001330707,0.002050555,0.0001019313,0.9290912,0.008064526,0.004253111,0.003003346],"study_design_scores_gemma":[0.001806864,0.00002415729,0.05243462,0.00001124495,0.0001572443,0.00004905646,0.0009372023,0.000006896062,0.6445853,0.0005160586,0.2992319,0.0002394413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9631722,0.03145424,0.00007856171,0.002377094,0.001033832,0.0002710546,0.0002008365,0.00007142968,0.001340756],"genre_scores_gemma":[0.9895269,0.001658129,0.0003069021,0.0004049958,0.00007721256,0.00006923015,0.0003207402,0.0000291544,0.007606789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2949788,"threshold_uncertainty_score":0.9993289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009271292545373802,"score_gpt":0.2438440822629258,"score_spread":0.234572789717552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}