{"id":"W3185088911","doi":"10.1158/1078-0432.ccr-21-2180","title":"Liquid Biopsy Goes Viral: Next-Generation Sequencing to Enhance HPV Detection","year":2021,"lang":"en","type":"letter","venue":"Clinical Cancer Research","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Liquid biopsy; DNA sequencing; Biopsy; DNA; Virology; Human papillomavirus; Papillomaviridae; Identification (biology); Medicine; Biology; Computational biology; Cancer; Pathology; Cervical cancer; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002350294,0.0007510397,0.000751054,0.001012705,0.0009415913,0.001600602,0.0009774407,0.01219385,0.004142693],"category_scores_gemma":[0.009155574,0.0004829103,0.0009393087,0.0004349656,0.001664812,0.002334593,0.0006327822,0.01328745,0.005851833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001864215,"about_ca_system_score_gemma":0.0008932763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00152632,"about_ca_topic_score_gemma":0.002919333,"domain_scores_codex":[0.9977908,0.0007293061,0.0001884287,0.0002216921,0.000902275,0.0001674087],"domain_scores_gemma":[0.9961411,0.002387611,0.0001673145,0.0001526651,0.0007618578,0.0003893293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003435938,0.0001593636,0.004471082,0.0003851397,0.00005453332,0.01813432,0.0002398359,0.0004201168,0.01221755,0.004530048,0.770904,0.1881404],"study_design_scores_gemma":[0.0001405092,0.0004336115,0.003484507,0.0005632713,0.00005176835,0.04181229,0.0002842812,0.00242205,0.006869209,0.0167328,0.9271324,0.00007332177],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.003580936,0.02323557,0.008992146,0.9078071,0.04036584,0.0001889782,0.0001599766,0.0003893031,0.01528011],"genre_scores_gemma":[0.03331145,0.03415621,0.01653892,0.7616017,0.118923,0.0002461605,0.0002223232,0.0001857366,0.03481444],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.01219385,"threshold_uncertainty_score":0.01385874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4692922918028105,"score_gpt":0.5522497215502418,"score_spread":0.08295742974743131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}