{"id":"W3185349989","doi":"10.1016/j.impact.2021.100343","title":"Low dose antibiotic ingestion potentiates systemic and microbiome changes induced by silver nanoparticles","year":2021,"lang":"en","type":"article","venue":"NanoImpact","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Environment and Climate Change Canada; McMaster University; Carleton University; Health Canada","funders":"Health Canada","keywords":"Microbiome; Akkermansia muciniphila; Antibiotics; Biology; Microbiology; Gut flora; Cecum; Ingestion; Metronidazole; Antimicrobial; Silver nanoparticle; Feces; Physiology; Immunology; Pharmacology; Endocrinology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001568897,0.0004590164,0.0005652442,0.000294055,0.0001121316,0.0002813184,0.0001617332,0.0005050491,0.001072513],"category_scores_gemma":[0.0002550638,0.0002067512,0.0003993846,0.0001547761,0.0003177244,0.0002034603,0.0003259926,0.0008876265,0.0002524244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001699722,"about_ca_system_score_gemma":0.0002358919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003791315,"about_ca_topic_score_gemma":0.0008112353,"domain_scores_codex":[0.9997316,0.00005189853,0.00001870527,0.00005270857,0.00006847444,0.00007655578],"domain_scores_gemma":[0.9997625,0.00003506204,0.00008142844,0.00002463213,0.00002581292,0.00007053478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009105699,0.0001592788,0.0005185551,0.00006444668,0.00001120444,0.00006477084,0.00001835146,0.0000504973,0.9956723,0.00001413059,0.00006779748,0.002448021],"study_design_scores_gemma":[0.0001137686,0.01260025,0.04765064,0.00004939889,0.000116221,0.000440213,0.0001164935,0.001430505,0.9337619,0.0001206874,0.003574603,0.0000253151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962583,0.001283031,0.0008886282,0.0001335194,0.00006294212,0.000046833,0.0002094486,0.00009388335,0.001023444],"genre_scores_gemma":[0.995437,0.001014217,0.001057277,0.0001781089,0.00003388057,0.00007768122,0.0003292995,0.00002501272,0.001847458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001072513,"threshold_uncertainty_score":0.003587961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01000410383591289,"score_gpt":0.2494280610822481,"score_spread":0.2394239572463353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}