{"id":"W3185349989","doi":"10.1016/j.impact.2021.100343","title":"Low dose antibiotic ingestion potentiates systemic and microbiome changes induced by silver nanoparticles","year":2021,"lang":"en","type":"article","venue":"NanoImpact","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Environment and Climate Change Canada; McMaster University; Carleton University; Health Canada","funders":"Health Canada","keywords":"Microbiome; Akkermansia muciniphila; Antibiotics; Biology; Microbiology; Gut flora; Cecum; Ingestion; Metronidazole; Antimicrobial; Silver nanoparticle; Feces; Physiology; Immunology; Pharmacology; Endocrinology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001352859,0.0001689755,0.0001807665,0.00004337698,0.0001081521,0.00006363713,0.00007483722,0.0002073735,0.00001536051],"category_scores_gemma":[0.0000491595,0.0001569753,0.00004301435,0.0001272439,0.00004327155,0.000006443589,0.00007866987,0.00007947606,0.00001647515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002653906,"about_ca_system_score_gemma":0.0001035064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004261363,"about_ca_topic_score_gemma":0.0000615868,"domain_scores_codex":[0.9989915,0.00008468483,0.0001592487,0.0003582506,0.00006692122,0.0003394002],"domain_scores_gemma":[0.9994712,0.000008767599,0.0000793688,0.0002365452,0.00007375623,0.0001302879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003495227,0.00007568245,0.001911408,0.000125765,0.00003463363,0.000007035532,0.00006640264,9.56018e-7,0.9942273,0.000003340198,0.001842318,0.001670135],"study_design_scores_gemma":[0.0005751502,0.0002136042,0.01468033,0.0001159456,0.00002469505,0.0001831088,0.00008946927,0.000004898432,0.9829785,0.000003550505,0.0009409334,0.0001898748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934068,0.005691345,0.000006799401,0.0004875341,0.0001551178,0.0001434907,0.00006053554,0.0000197713,0.00002860087],"genre_scores_gemma":[0.9979752,0.0009245652,0.00006936866,0.0004481385,0.00008464925,0.000002127416,0.0002210871,0.00002391557,0.0002508966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01276892,"threshold_uncertainty_score":0.6401268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01000410383591289,"score_gpt":0.2494280610822481,"score_spread":0.2394239572463353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}