{"id":"W3185437491","doi":"10.1016/s2213-8587(21)00174-1","title":"Efficacy and safety of once-weekly semaglutide 2·0 mg versus 1·0 mg in patients with type 2 diabetes (SUSTAIN FORTE): a double-blind, randomised, phase 3B trial","year":2021,"lang":"en","type":"article","venue":"The Lancet Diabetes & Endocrinology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":176,"is_retracted":false,"has_abstract":false,"ca_institutions":"LMC Diabetes & Endocrinology (Canada)","funders":"Novo Nordisk","keywords":"Semaglutide; Medicine; Discontinuation; Type 2 diabetes; Sulfonylurea; Internal medicine; Randomized controlled trial; Diabetes mellitus; Metformin; Physical therapy; Insulin; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00177247,0.002339024,0.004796997,0.0004870282,0.0004399196,0.001587744,0.001295233,0.002727459,0.009337678],"category_scores_gemma":[0.001842499,0.001045648,0.002857837,0.0004480042,0.001613174,0.001872238,0.0005228457,0.004328544,0.001818654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008057303,"about_ca_system_score_gemma":0.0007986386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001126364,"about_ca_topic_score_gemma":0.001627785,"domain_scores_codex":[0.9993792,0.0002956674,0.00003618068,0.0001388798,0.00004119597,0.0001087797],"domain_scores_gemma":[0.9990265,0.0003138979,0.0001998147,0.00008727585,0.00004703148,0.00032538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.991042,0.001514156,0.0002136528,0.0002583191,0.0004895593,0.00001677701,0.00002493555,0.000126373,0.0008954799,0.00004466758,0.0003753295,0.004998672],"study_design_scores_gemma":[0.9707211,0.02743867,0.0008733523,0.0000185082,0.0002832049,0.00001738434,0.00001547115,0.0002384697,0.0001069089,0.00009047837,0.000183688,0.0000127608],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863124,0.00674543,0.0005116562,0.0009560674,0.000886999,0.001125333,0.001024842,0.0002528779,0.00218434],"genre_scores_gemma":[0.986893,0.002946746,0.001054898,0.001520777,0.0007114158,0.001479954,0.001328373,0.00006009602,0.004004866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009337678,"threshold_uncertainty_score":0.0312376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03327913042604658,"score_gpt":0.3050845420511496,"score_spread":0.271805411625103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}