{"id":"W3185621609","doi":"10.1192/j.eurpsy.2021.2222","title":"Transition to psychosis in randomized clinical trials of individuals at clinical high risk of psychosis compared to observational cohorts: a systematic review and meta-analysis","year":2021,"lang":"en","type":"review","venue":"European Psychiatry","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Observational study; Meta-analysis; Randomized controlled trial; Psychosis; Medicine; Confidence interval; Systematic review; Publication bias; Relative risk; Epidemiology; Internal medicine; Psychiatry; MEDLINE; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","metaepi_broad"],"consensus_categories":["metaresearch","metaepi_broad"],"category_scores_codex":[0.0680738,0.0007658059,0.04459037,0.001082147,0.00005428239,0.00003202901,0.0004285524,0.0002614131,0.0007427453],"category_scores_gemma":[0.01457572,0.0004730608,0.01523818,0.002671996,0.0001613134,0.00004389101,0.0001449823,0.0007044467,0.00007736807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007656932,"about_ca_system_score_gemma":0.0004068724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008309865,"about_ca_topic_score_gemma":0.0002089918,"domain_scores_codex":[0.9290338,0.05391849,0.01425502,0.001313279,0.00113325,0.0003461307],"domain_scores_gemma":[0.9819174,0.01050923,0.004682626,0.00172125,0.000433108,0.000736378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.01122185,0.002210919,0.003063824,0.4159684,0.5533361,0.00002305963,0.0001006089,0.000003242787,1.34357e-8,0.0001387508,0.008682992,0.00525019],"study_design_scores_gemma":[0.03145847,0.0003567315,0.001910855,0.1126579,0.8510544,0.00001522433,0.0000177497,0.000002548264,4.294651e-8,0.0000387659,0.002194915,0.0002924621],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005145737,0.9789376,0.0002243779,0.003228739,0.0002773513,0.01467048,0.002071491,0.00002203296,0.00005332676],"genre_scores_gemma":[0.0002327302,0.9737422,0.0217463,0.001420059,0.0001621957,0.001295345,0.001213771,0.00008589251,0.0001015215],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3033106,"threshold_uncertainty_score":0.9997721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3442770530867572,"score_gpt":0.5126298293825117,"score_spread":0.1683527762957545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}