{"id":"W3185751141","doi":"10.1007/s40263-021-00840-x","title":"Safety, Patient-Reported Well-Being, and Physician-Reported Assessment of Walking Ability in Patients with Multiple Sclerosis for Prolonged-Release Fampridine Treatment in Routine Clinical Practice: Results of the LIBERATE Study","year":2021,"lang":"en","type":"article","venue":"CNS Drugs","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"EMD Serono; Teva Pharmaceutical Industries; Celgene; MedDay Pharmaceuticals; Biogen; Sanofi","keywords":"Medicine; Adverse effect; Multiple sclerosis; Incidence (geometry); Clinical Practice; Expanded Disability Status Scale; Physical therapy; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001851263,0.0002849607,0.001000775,0.0001163043,0.0001059828,0.0000160888,0.00009695654,0.00008412303,0.000003484258],"category_scores_gemma":[0.006615525,0.0001838155,0.0001518501,0.0006610788,0.0002300483,0.0001396511,0.0002596274,0.000324126,1.901282e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003361913,"about_ca_system_score_gemma":0.0004900414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007071653,"about_ca_topic_score_gemma":0.0008639292,"domain_scores_codex":[0.9953784,0.0007287821,0.001920428,0.0007622533,0.0008279679,0.0003821587],"domain_scores_gemma":[0.9950374,0.001726716,0.001072618,0.0008963427,0.001145866,0.0001210195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006136375,0.01586333,0.9462493,0.0001328367,0.0006469998,0.00001944942,0.005558576,0.00009869473,0.0008870749,0.000001624054,0.00002536674,0.02438036],"study_design_scores_gemma":[0.03867494,0.003021925,0.9496228,0.0005190021,0.0003100579,8.272731e-7,0.003635728,0.001281571,0.002687984,0.000004540206,0.00009783125,0.0001428213],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928322,0.00005190795,0.000007141554,0.0008538323,0.00008034906,0.005771099,0.00007148887,0.00001645408,0.0003155493],"genre_scores_gemma":[0.9982247,0.0001229618,0.001052246,0.00006594005,0.00002900657,0.0003444324,0.00008871459,0.00003005354,0.0000418928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03253856,"threshold_uncertainty_score":0.791988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0465823873557548,"score_gpt":0.3607522575652409,"score_spread":0.3141698702094861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}