{"id":"W3185751141","doi":"10.1007/s40263-021-00840-x","title":"Safety, Patient-Reported Well-Being, and Physician-Reported Assessment of Walking Ability in Patients with Multiple Sclerosis for Prolonged-Release Fampridine Treatment in Routine Clinical Practice: Results of the LIBERATE Study","year":2021,"lang":"en","type":"article","venue":"CNS Drugs","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"EMD Serono; Teva Pharmaceutical Industries; Celgene; MedDay Pharmaceuticals; Biogen; Sanofi","keywords":"Medicine; Adverse effect; Multiple sclerosis; Incidence (geometry); Clinical Practice; Expanded Disability Status Scale; Physical therapy; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005434569,0.0004104827,0.0008658552,0.000454591,0.0002683139,0.000790706,0.0003130844,0.0005828192,0.0008969094],"category_scores_gemma":[0.007591368,0.0002152435,0.001044596,0.000758447,0.0003105356,0.0005668678,0.0005165733,0.0006701413,0.0002277997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003497232,"about_ca_system_score_gemma":0.0003347126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007214844,"about_ca_topic_score_gemma":0.001070293,"domain_scores_codex":[0.997359,0.001519737,0.0002914197,0.0002544201,0.0004726884,0.0001026754],"domain_scores_gemma":[0.9922008,0.002062505,0.003985504,0.0004003809,0.0007463726,0.0006044906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01552742,0.0008442758,0.9664553,0.0001742193,0.000932863,0.00007667012,0.0003012425,0.0001664158,0.0005055498,0.0000146329,0.0003354584,0.0146658],"study_design_scores_gemma":[0.001893551,0.006595155,0.9897302,0.00003570825,0.0003699259,0.0002178676,0.0001243727,0.0004210015,0.0001439184,0.00001395543,0.0004363925,0.00001794933],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998069,0.0007970297,0.00008649073,0.00007754383,0.000007266567,0.00007028864,0.0004952704,0.000004326867,0.0003927304],"genre_scores_gemma":[0.9987821,0.0002346194,0.000138472,0.00008149551,0.00001995789,0.0000579646,0.0005932754,0.000001719686,0.00009036607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005434569,"threshold_uncertainty_score":0.02874112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0465823873557548,"score_gpt":0.3607522575652409,"score_spread":0.3141698702094861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}