{"id":"W3185985271","doi":"10.1101/2021.07.29.454218","title":"A cohesin traffic pattern genetically linked to gene regulation","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute","keywords":"Cohesin; CTCF; Chromatin; Transcription (linguistics); RNA polymerase II; RNA; General transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004081292,0.0002343641,0.0001419145,0.000419294,0.0001633704,0.0002756048,0.0001865725,0.0002808194,0.001694784],"category_scores_gemma":[0.0001038262,0.0001351165,0.0001370961,0.0001753592,0.000304969,0.0001015443,0.0002917539,0.0005533097,0.0002852325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000617848,"about_ca_system_score_gemma":0.0001963593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001056344,"about_ca_topic_score_gemma":0.001272235,"domain_scores_codex":[0.9999024,0.00001003272,0.000008188503,0.00003473219,0.00002860416,0.00001597326],"domain_scores_gemma":[0.9997432,0.00004295464,0.00009466081,0.00003167609,0.00002447136,0.00006311027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005043799,0.00001305243,0.0002905566,0.000007345471,0.000003105911,0.00005534227,0.000006782019,0.00008689622,0.9984657,0.0002362407,0.00003319812,0.0007513586],"study_design_scores_gemma":[0.00002939547,0.0001577848,0.01924039,0.00001137483,0.00002517178,0.0008699683,0.00004228808,0.003013717,0.9739138,0.0003997445,0.002281314,0.00001507563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949654,0.000301435,0.002592166,0.0001160019,0.00002432419,0.0000204468,0.0004361312,0.0001236458,0.00142041],"genre_scores_gemma":[0.9955142,0.0001154733,0.000753063,0.00003338767,0.000003717465,0.00002249638,0.0002866847,0.00002709314,0.003243964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001694784,"threshold_uncertainty_score":0.005669653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007841099492970178,"score_gpt":0.2026594592496638,"score_spread":0.1948183597566936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}