{"id":"W3185994964","doi":"10.1159/000516490","title":"Baseline Liver Function and Subsequent Outcomes in the Phase 3 REFLECT Study of Patients with Unresectable Hepatocellular Carcinoma","year":2021,"lang":"en","type":"article","venue":"Liver Cancer","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Eisai","keywords":"Lenvatinib; Sorafenib; Medicine; Hepatocellular carcinoma; Internal medicine; Liver function; Adverse effect; Oncology; Overall survival; Post-hoc analysis; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001999582,0.0001763826,0.0003445513,0.00008761208,0.00006033813,0.00001757123,0.00005675741,0.00005042249,0.0003218474],"category_scores_gemma":[0.0000200733,0.0001069983,0.00005573958,0.0003409138,0.00003834174,0.00008599725,0.0000346601,0.0001409876,0.000002876838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008595066,"about_ca_system_score_gemma":0.0001125154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002354113,"about_ca_topic_score_gemma":0.001248494,"domain_scores_codex":[0.9986406,0.0002119358,0.0002301308,0.0003129908,0.0004033083,0.0002010142],"domain_scores_gemma":[0.9992771,0.00008309575,0.00007504565,0.0003090469,0.0001887999,0.00006689504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000944351,0.00319348,0.9907148,0.00009654256,0.0001924235,0.0005784102,0.00175229,9.872749e-7,0.0002352883,0.000008996399,0.00006302114,0.002219392],"study_design_scores_gemma":[0.01200914,0.002528037,0.9804742,0.00005242986,0.0006707045,0.000005502026,0.0007008342,0.001114412,0.001913229,0.000004463474,0.0004022341,0.000124777],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947729,0.003773143,0.00002145491,0.0001286817,0.00005634088,0.001096438,0.00003205083,0.00001173548,0.0001072537],"genre_scores_gemma":[0.9990334,0.0001555762,0.00004648205,0.0002234913,0.00003860586,0.0001742208,0.00008576921,0.00001898396,0.0002234643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01106479,"threshold_uncertainty_score":0.4363265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05933619209472887,"score_gpt":0.2809289060137234,"score_spread":0.2215927139189945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}