{"id":"W3185994964","doi":"10.1159/000516490","title":"Baseline Liver Function and Subsequent Outcomes in the Phase 3 REFLECT Study of Patients with Unresectable Hepatocellular Carcinoma","year":2021,"lang":"en","type":"article","venue":"Liver Cancer","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Eisai","keywords":"Lenvatinib; Sorafenib; Medicine; Hepatocellular carcinoma; Internal medicine; Liver function; Adverse effect; Oncology; Overall survival; Post-hoc analysis; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002918689,0.0005079008,0.0005939928,0.0003213768,0.000264878,0.0006668519,0.0003700527,0.0003561163,0.001133493],"category_scores_gemma":[0.00225524,0.0002943021,0.0007501653,0.0005263115,0.0002332681,0.0004912988,0.0004751631,0.0009746631,0.000327259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004935558,"about_ca_system_score_gemma":0.000469813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007542289,"about_ca_topic_score_gemma":0.001354375,"domain_scores_codex":[0.9991258,0.0005070897,0.00005686302,0.000100474,0.000129154,0.00008074562],"domain_scores_gemma":[0.9980614,0.0002759185,0.0008942071,0.0001764481,0.0002115083,0.0003805374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.06016966,0.002957409,0.9122477,0.0001449325,0.001889281,0.0001294203,0.0001114403,0.0009950799,0.004288273,0.00008600581,0.00238623,0.01459463],"study_design_scores_gemma":[0.005299159,0.01431883,0.9764178,0.00001501677,0.0005747324,0.000318954,0.00006815129,0.00111238,0.0007622217,0.00007079398,0.00101693,0.00002483453],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979905,0.0004573398,0.00010463,0.0001398134,0.00001079039,0.00007393779,0.0007485377,0.00000890955,0.0004655757],"genre_scores_gemma":[0.9975652,0.0001451941,0.000138703,0.0001222255,0.00003421198,0.00008293356,0.001700946,0.000004789394,0.0002058161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002918689,"threshold_uncertainty_score":0.0154357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05933619209472887,"score_gpt":0.2809289060137234,"score_spread":0.2215927139189945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}