{"id":"W3186036406","doi":"10.1097/pas.0000000000001753","title":"Impact of Next-generation Sequencing on Interobserver Agreement and Diagnosis of Spitzoid Neoplasms","year":2021,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Melanoma; Genomics; Differential diagnosis; Genomic sequencing; Metastatic melanoma; Melanoma diagnosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1148931,0.0006391832,0.0008538117,0.002354252,0.0008557938,0.001366416,0.001034366,0.00115513,0.0007721934],"category_scores_gemma":[0.1989973,0.0006004013,0.001285328,0.0008818758,0.001453595,0.00143043,0.002863038,0.0009140056,0.0003372716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009440923,"about_ca_system_score_gemma":0.0005518066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001485529,"about_ca_topic_score_gemma":0.003341498,"domain_scores_codex":[0.8174955,0.1364944,0.01440065,0.01219957,0.01741078,0.001999059],"domain_scores_gemma":[0.5749341,0.3726729,0.01270586,0.01525534,0.02275423,0.00167755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004685745,0.0001591386,0.8499752,0.0009006549,0.002641792,0.0005491859,0.00831762,0.008378603,0.01755353,0.0005186943,0.0009960276,0.1053238],"study_design_scores_gemma":[0.0001253533,0.00168021,0.9211753,0.0003454277,0.0009818168,0.002231832,0.003043049,0.04533625,0.0202201,0.002022473,0.002624973,0.0002133401],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9639899,0.003588906,0.02640802,0.0003918665,0.0002773944,0.0001861896,0.0001896141,0.0002469056,0.004721276],"genre_scores_gemma":[0.9929248,0.0001357684,0.006436864,0.00009590698,0.00003863583,0.0000475382,0.00008296955,0.00002463198,0.000212972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1148931,"threshold_uncertainty_score":0.6076203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05412592064391949,"score_gpt":0.2995960924908104,"score_spread":0.2454701718468909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}