{"id":"W3186062956","doi":"10.2147/jpr.s321841","title":"One-Year, Efficacy and Safety Open Label Study, with a Single Injection of a New Hyaluronan for Knee OA: The SOYA Trial","year":2021,"lang":"en","type":"article","venue":"Journal of Pain Research","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Osteoarthritis; WOMAC; Visual analogue scale; Adverse effect; Viscosupplementation; Clinical endpoint; Physical therapy; Knee pain; Surgery; Randomized controlled trial; Internal medicine; Intra articular","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002522272,0.001613649,0.003530638,0.0004174557,0.0006072648,0.001295697,0.0008137077,0.00252456,0.003669004],"category_scores_gemma":[0.001281499,0.0007184015,0.002244513,0.0004321494,0.001362995,0.001308967,0.0004832386,0.002811674,0.001154271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004833648,"about_ca_system_score_gemma":0.0007447625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000476651,"about_ca_topic_score_gemma":0.0009048281,"domain_scores_codex":[0.999171,0.0003467661,0.00005807671,0.0001748013,0.0001099417,0.0001394266],"domain_scores_gemma":[0.9986236,0.000243739,0.0004010734,0.0001254651,0.0001052065,0.0005009004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9560817,0.02072333,0.003047132,0.0005423859,0.001097907,0.00008267798,0.0001012256,0.000205806,0.004515249,0.00003395963,0.0002848198,0.01328373],"study_design_scores_gemma":[0.6739477,0.3110445,0.01285411,0.00003826482,0.0005313586,0.0000902183,0.00004314696,0.0002824509,0.0006351335,0.00004744079,0.0004621646,0.00002352253],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949208,0.002736855,0.0003262605,0.0002475411,0.0001391488,0.0007252456,0.0003979437,0.00003189576,0.0004743206],"genre_scores_gemma":[0.9920446,0.001793043,0.0005948895,0.00074535,0.0004778422,0.001434556,0.0009103559,0.00001254834,0.001986779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003669004,"threshold_uncertainty_score":0.01333922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1764043079681353,"score_gpt":0.4191410932125184,"score_spread":0.242736785244383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}