{"id":"W3186441708","doi":"10.1016/j.copbio.2021.06.022","title":"Cytochromes P450 in the biocatalytic valorization of lignin","year":2021,"lang":"en","type":"review","venue":"Current Opinion in Biotechnology","topic":"Lignin and Wood Chemistry","field":"Engineering","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council; National Renewable Energy Laboratory; Research England; Natural Sciences and Engineering Research Council of Canada; Genome British Columbia; University of Portsmouth; Genome Canada; U.S. Department of Energy","keywords":"Lignin; Chemistry; Biochemical engineering; Organic chemistry; Depolymerization; Metabolic engineering; Biorefinery; Biotechnology; Enzyme; Raw material; Biology; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001580899,0.0002748851,0.0008718857,0.0004297149,0.00001087745,0.00001088421,0.0005463451,0.0007916577,0.000003687097],"category_scores_gemma":[0.00005090819,0.0002172378,0.0001487094,0.001275857,0.00009124137,0.00002744884,0.00009599714,0.0007720459,0.00001476005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001059572,"about_ca_system_score_gemma":0.0000761152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001887037,"about_ca_topic_score_gemma":6.841994e-7,"domain_scores_codex":[0.9986915,0.00005000942,0.0006364297,0.0002732956,0.0001192481,0.0002294953],"domain_scores_gemma":[0.9992558,0.00009248623,0.0001147412,0.0005070627,0.00001446936,0.00001543677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[3.415648e-7,0.0001740514,0.00001352883,0.07393894,0.00007156443,0.000005074606,0.0001465227,0.00001800429,0.0002328797,0.003848976,0.01528902,0.9062611],"study_design_scores_gemma":[0.0001486374,0.0000146674,0.000002270674,0.01963703,0.00003406674,0.00002774163,0.00006254701,0.00003847505,0.003832378,0.00007959337,0.9758556,0.0002669836],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001326989,0.9978117,0.00003510409,0.00004094928,0.001526345,0.000313205,0.00002992958,0.00009816435,0.0001312781],"genre_scores_gemma":[0.0006102882,0.9986244,0.00003462016,9.769997e-7,0.000135398,0.0001098096,0.0004524053,0.00002943278,0.000002611319],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9605666,"threshold_uncertainty_score":0.8858702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0691203597970661,"score_gpt":0.3512661311636056,"score_spread":0.2821457713665395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}