{"id":"W3186467046","doi":"10.5530/ijpi.2021.2.35","title":"Provesicular Based Colloidal Carriers for Transdermal Drug Delivery: Formulation Aspects and Bioavailability Enhancement of Acyclovir Proliposomal Gels","year":2021,"lang":"en","type":"article","venue":"International Journal of Pharmaceutical Investigation","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Bioavailability; Permeation; Transdermal; Zeta potential; Chromatography; Chemistry; Liposome; Pharmacology; Drug; Pharmacokinetics; Materials science; Membrane; Nanoparticle; Nanotechnology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003385308,0.0001148117,0.0002226797,0.0001272507,0.00004897973,0.00002699789,0.00005401141,0.00006015162,0.00008316206],"category_scores_gemma":[0.0002062517,0.0001013997,0.0001474037,0.0001122941,0.0001166568,0.0002502254,0.00001400981,0.0001372618,9.208871e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002189495,"about_ca_system_score_gemma":0.000562232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001157766,"about_ca_topic_score_gemma":0.000005545638,"domain_scores_codex":[0.9986559,0.00007052424,0.0005337544,0.0001564454,0.000451596,0.0001318515],"domain_scores_gemma":[0.9981373,0.0001266937,0.0002425435,0.0000697014,0.001212728,0.0002110299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001592554,0.001010779,0.04759176,0.0002940776,0.001074188,0.00008922223,0.0003947212,0.0001733281,0.9211769,0.001279545,0.0001771557,0.02514582],"study_design_scores_gemma":[0.005201744,0.0002635759,0.008569065,0.0001390818,0.0003557137,0.00008252267,0.00003371153,0.00718766,0.9726925,0.001121091,0.004269992,0.00008329805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904792,0.0002126057,0.00505189,0.003366622,0.0003113203,0.0004358091,0.00004068195,0.000007963922,0.00009391594],"genre_scores_gemma":[0.9918127,0.00004073796,0.007336088,0.0005536967,0.0001588092,0.00001909188,0.00004251227,0.00001059672,0.00002576748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0515157,"threshold_uncertainty_score":0.413496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03170383724858691,"score_gpt":0.3372912557027903,"score_spread":0.3055874184542035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}