{"id":"W3186530209","doi":"10.1016/j.nano.2021.102441","title":"Human astrocytes and astrocytoma respond differently to resveratrol","year":2021,"lang":"en","type":"article","venue":"Nanomedicine Nanotechnology Biology and Medicine","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Resveratrol; Viability assay; Astrocytoma; Temozolomide; Cancer research; Population; Chemistry; Pharmacology; Glutathione; Reactive oxygen species; Cell; Medicine; Glioma; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006445522,0.0005378962,0.00157878,0.0009345684,0.0003872121,0.00000925952,0.0001797657,0.0009021345,0.0004326772],"category_scores_gemma":[0.001346145,0.0003675705,0.0000741876,0.0008043209,0.002060649,0.00004888752,0.0003049441,0.001041808,0.00001490852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007429265,"about_ca_system_score_gemma":0.000159802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004156991,"about_ca_topic_score_gemma":0.00004477863,"domain_scores_codex":[0.9967712,0.0001527822,0.0008077379,0.001134081,0.0003118842,0.0008222684],"domain_scores_gemma":[0.9978163,0.0002489706,0.0001617445,0.0007514535,0.0003016074,0.0007199239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001080021,0.0001723186,0.04704601,0.0001560666,0.0003252038,0.001030034,0.0004257967,1.907434e-7,0.9010889,0.008474292,0.004867808,0.03533334],"study_design_scores_gemma":[0.06506263,0.06173419,0.3747765,0.003757098,0.002539892,0.02266937,0.008337072,0.00008213223,0.165857,0.004925148,0.2884988,0.001760069],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.913558,0.01373924,0.0005586656,0.0698918,0.0005158618,0.000570966,0.00001232218,0.0002453627,0.0009077466],"genre_scores_gemma":[0.9825159,0.001537941,0.001634804,0.009869037,0.0010834,0.00006705456,0.0001189057,0.00004826869,0.003124745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7352319,"threshold_uncertainty_score":0.9998776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01462216067315808,"score_gpt":0.3223999754349395,"score_spread":0.3077778147617814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}