{"id":"W3186657611","doi":"10.3389/fmicb.2021.703421","title":"Pathogen Challenge and Dietary Shift Alter Microbiota Composition and Activity in a Mucin-Associated in vitro Model of the Piglet Colon (MPigut-IVM) Simulating Weaning Transition","year":2021,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Lallemand; Agence Nationale de la Recherche","keywords":"Weaning; Biology; Enterotoxigenic Escherichia coli; Microbiology; Lachnospiraceae; Gut flora; Microbiome; Pathogen; Immunology; Butyrate; Food science; Animal science; Firmicutes; Escherichia coli; Enterotoxin; Bacteria; Biochemistry; Bioinformatics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002647578,0.0004342505,0.0003555382,0.0001739328,0.00014064,0.0003265205,0.000218614,0.0005048241,0.0006864615],"category_scores_gemma":[0.0001430698,0.0001663529,0.0003384907,0.000111934,0.0002192072,0.0002143878,0.0002725802,0.0006508935,0.0001606588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000206244,"about_ca_system_score_gemma":0.0002137057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006266258,"about_ca_topic_score_gemma":0.0007866384,"domain_scores_codex":[0.9997614,0.00005900634,0.00001856968,0.0000582006,0.00004454754,0.00005824797],"domain_scores_gemma":[0.9998479,0.00003305516,0.00004694256,0.00001638901,0.00001380566,0.0000418544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003084439,0.0001378069,0.0004682791,0.00004200215,0.000004420109,0.00007996708,0.00002933439,0.0001167656,0.9982693,0.00001905833,0.00001690292,0.0005075823],"study_design_scores_gemma":[0.00006656236,0.01025633,0.03934082,0.00003286866,0.00007240057,0.0004193584,0.0002511623,0.004212781,0.9430029,0.0001208636,0.002194844,0.00002908332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973369,0.000413985,0.001346892,0.00006805801,0.00004070834,0.00004268333,0.0002004541,0.00002122879,0.0005291184],"genre_scores_gemma":[0.9935858,0.0005343074,0.004135396,0.0001326847,0.00001622279,0.00009675342,0.0004178953,0.00001003609,0.001070977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006864615,"threshold_uncertainty_score":0.002296448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01035236176576014,"score_gpt":0.2293175370111695,"score_spread":0.2189651752454094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}