{"id":"W3186813330","doi":"10.3390/md19080408","title":"Anti-Cancer and Anti-Inflammatory Activities of Three New Chromone Derivatives from the Marine-Derived Penicillium citrinum","year":2021,"lang":"en","type":"article","venue":"Marine Drugs","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Beef Cattle Research Council; Ministry of Science and Technology, Taiwan","keywords":"Penicillium citrinum; Chromone; Apoptosis; Chemistry; Superoxide; IC50; Western blot; Stereochemistry; HeLa; Cytotoxic T cell; Cancer cell; Biochemistry; Biology; Cancer; Cell; In vitro; Gene; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005079596,0.0003162475,0.0001782754,0.0002548054,0.00009299302,0.000125482,0.0001465398,0.0001866718,0.0008499949],"category_scores_gemma":[0.00006735526,0.00006967801,0.0001366719,0.000125316,0.0001450071,0.0001389854,0.0001406431,0.0002792999,0.0001438474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001225896,"about_ca_system_score_gemma":0.000149892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004668763,"about_ca_topic_score_gemma":0.001095634,"domain_scores_codex":[0.999975,0.00000404405,0.000003107588,0.00000500715,0.000006678407,0.000006266446],"domain_scores_gemma":[0.999971,0.000002926089,0.000007138849,0.000002689039,0.000004383654,0.00001173053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002709159,0.00005849603,0.0004771974,0.000172929,0.00001583019,0.0002745344,0.00002300284,0.0003528891,0.987917,0.0001433925,0.0001034694,0.01019043],"study_design_scores_gemma":[0.00009928053,0.002087132,0.01125939,0.00002681875,0.0000595743,0.001065616,0.00003621506,0.0005410335,0.9773501,0.00008947556,0.007367932,0.00001758187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859574,0.008044302,0.001863615,0.0001083193,0.0000320022,0.00004864903,0.0005512339,0.0000613879,0.00333307],"genre_scores_gemma":[0.9946589,0.002548592,0.001142333,0.00008380812,0.00001244158,0.00001311137,0.0004357366,0.000004110077,0.001100981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008499949,"threshold_uncertainty_score":0.002843499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06532037200022088,"score_gpt":0.3517045169667382,"score_spread":0.2863841449665173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}