{"id":"W3186838762","doi":"10.1002/jez.2507","title":"Hif‐1α is not required for the development of cardiac adrenergic control in zebrafish (<i>Danio rerio</i>)","year":2021,"lang":"en","type":"article","venue":"Journal of Experimental Zoology Part A Ecological and Integrative Physiology","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Novo Nordisk Fonden","keywords":"Zebrafish; Danio; Biology; Endocrinology; Internal medicine; Cardiac function curve; Tyrosine hydroxylase; Heart development; Adrenergic; Heart rate; Anatomy; Receptor; Medicine; Heart failure; Blood pressure; Gene; Dopamine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002561884,0.0001920398,0.0006561727,0.00002258353,0.0001418814,0.000007034002,0.000230418,0.0001670997,0.001136104],"category_scores_gemma":[0.0002183827,0.00009820946,0.0002189517,0.0001553071,0.00079458,0.00009173239,0.0001993461,0.0002463848,0.000008708353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009738858,"about_ca_system_score_gemma":0.00005203994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008361443,"about_ca_topic_score_gemma":0.00002944988,"domain_scores_codex":[0.9983469,0.0002400444,0.0007063767,0.0003052545,0.0001177435,0.0002837059],"domain_scores_gemma":[0.9985758,0.0008276211,0.0003353495,0.0001039773,0.00006815158,0.00008910778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005274686,0.0005813946,0.001061331,0.000002751294,0.00008688856,0.000003252586,0.0006167665,0.00002418734,0.9947631,0.0005605025,0.001186283,0.0005860097],"study_design_scores_gemma":[0.001125755,0.001448081,0.1788583,0.00001683857,0.00002958511,0.00001442462,0.002099715,0.0002116419,0.8087867,0.00384828,0.003391315,0.0001692975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974684,0.0006960077,0.0001201956,0.0008711117,0.0002492757,0.0002013843,0.00002401363,0.000003891193,0.000365692],"genre_scores_gemma":[0.9962163,0.00009626547,0.001700419,0.001727659,0.00007673902,0.00007864687,0.000008886501,0.000004636914,0.00009042647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1859764,"threshold_uncertainty_score":0.999777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02593865374902271,"score_gpt":0.2681026544866686,"score_spread":0.2421640007376459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}