{"id":"W3186898810","doi":"10.3389/fimmu.2021.697683","title":"Employing Broadly Neutralizing Antibodies as a Human Immunodeficiency Virus Prophylactic & Therapeutic Application","year":2021,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Fundamental Research Funds for the Central Universities; Canadian Institutes of Health Research","keywords":"Human immunodeficiency virus (HIV); Virology; Immunology; Antibody; HIV vaccine; Medicine; Virus; Immunodeficiency; Biology; Immune system; Vaccine trial","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003173935,0.0005679779,0.0006998922,0.001391986,0.0001668996,0.000701657,0.0005021919,0.000793278,0.00313065],"category_scores_gemma":[0.0003014544,0.0001581295,0.0003466488,0.0009690607,0.0002744539,0.0006770667,0.0004128703,0.001498361,0.002069423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003570598,"about_ca_system_score_gemma":0.000473684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004301514,"about_ca_topic_score_gemma":0.0007263425,"domain_scores_codex":[0.9998819,0.00002094627,0.00001122787,0.00002194983,0.00004882221,0.0000151163],"domain_scores_gemma":[0.9999057,0.00003883276,0.00001391206,0.000003684709,0.00002656826,0.00001121033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006923326,0.0001164369,0.0001324015,0.01007978,0.00004668947,0.0001882641,0.00004579034,0.0002413542,0.008925261,0.004537024,0.01958696,0.9560308],"study_design_scores_gemma":[0.00001358174,0.0001573756,0.0004501286,0.001413919,0.00005511626,0.001004859,0.0000301659,0.00007993179,0.002166384,0.001208423,0.993408,0.00001212739],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003708379,0.9958358,0.0003797789,0.0002793694,0.0003145852,0.00001228729,0.00002882963,0.00001480505,0.002763613],"genre_scores_gemma":[0.001884912,0.9955239,0.0004521256,0.0003104736,0.0001720042,0.00001590053,0.00004971581,0.00000249428,0.001588482],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00313065,"threshold_uncertainty_score":0.01047307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04519500035498498,"score_gpt":0.3533522026791805,"score_spread":0.3081572023241956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}