{"id":"W3187145316","doi":"10.1093/jpids/piab024","title":"Comparative Effectiveness of Echinocandins vs Triazoles or Amphotericin B Formulations as Initial Directed Therapy for Invasive Candidiasis in Children and Adolescents","year":2021,"lang":"en","type":"article","venue":"Journal of the Pediatric Infectious Diseases Society","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Echinocandin; Medicine; Echinocandins; Amphotericin B; Caspofungin; Internal medicine; Anidulafungin; Antifungal; Fluconazole; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000291611,0.000147842,0.0005994662,0.00007219103,0.0001467558,0.00002159684,0.00007062807,0.00008403324,0.00001174381],"category_scores_gemma":[0.0006595405,0.00009267095,0.0005193395,0.0005501733,0.00009086644,0.0001329727,0.0000349428,0.0002083373,1.774201e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001985649,"about_ca_system_score_gemma":0.00122189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001058427,"about_ca_topic_score_gemma":0.000114454,"domain_scores_codex":[0.9987455,0.0002634833,0.0004277243,0.0001550504,0.0002449291,0.0001633121],"domain_scores_gemma":[0.9982026,0.000700548,0.0003981711,0.0001408894,0.0004503909,0.0001073812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003843823,0.0008129554,0.9931942,0.0003061208,0.0002437287,0.000003714773,0.000724135,0.00005167536,0.0005486991,0.000007735591,0.0001317989,0.00013143],"study_design_scores_gemma":[0.008148957,0.0006350414,0.9878759,0.0002097673,0.0005482231,0.0001525662,0.000287137,0.00002880133,0.001619574,0.0003989627,0.000001239738,0.00009387737],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975096,0.00114966,0.0001945298,0.00003417086,0.0001373434,0.0008271949,0.0001252258,0.0000102972,0.00001198379],"genre_scores_gemma":[0.9971538,0.00241027,0.00005436609,0.0001128031,0.0002225192,0.00001314313,0.00001428671,0.00001146906,0.00000731323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005318332,"threshold_uncertainty_score":0.3779011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01554565724513514,"score_gpt":0.3140895721172925,"score_spread":0.2985439148721574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}