{"id":"W3187427232","doi":"10.1016/j.jbc.2021.100987","title":"CD147 mediates the CD44s-dependent differentiation of myofibroblasts driven by transforming growth factor-β1","year":2021,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Cardiff University","keywords":"Myofibroblast; CD44; Cell biology; Transforming growth factor; Proinflammatory cytokine; Extracellular matrix; Fibroblast; Biology; Fibrosis; Cancer research; Immunology; Cell culture; Cell; Pathology; Inflammation; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001494478,0.0001526797,0.0002327262,0.000008347204,0.0000478712,0.00001784344,0.0003213845,0.0002445097,0.0001190954],"category_scores_gemma":[0.0005075576,0.00009491923,0.0002581143,0.00006548243,0.0001178499,0.00000508207,0.00007833521,0.0002156124,6.880608e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001998834,"about_ca_system_score_gemma":0.0001016653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.331117e-7,"about_ca_topic_score_gemma":4.320722e-7,"domain_scores_codex":[0.9988614,0.00007449793,0.000456527,0.0001885864,0.0002420613,0.0001769233],"domain_scores_gemma":[0.9990121,0.00006897657,0.0003535158,0.0001750039,0.0002768627,0.0001135728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008866403,0.0001307965,0.008774365,0.0000413336,0.0001034618,0.00001166862,0.00003413147,0.00001304778,0.9899114,0.00000286303,0.0005791594,0.0003091233],"study_design_scores_gemma":[0.0004506703,0.0001317592,0.002380414,0.00003947214,0.00003364614,0.00006174622,0.0001200004,0.000009484326,0.9961666,0.0001143867,0.0003773656,0.000114463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966272,0.001744479,0.0009775533,0.000216104,0.0001373058,0.00004301879,0.00007598084,0.000004524494,0.0001738594],"genre_scores_gemma":[0.9988709,0.0004546169,0.0001114787,0.00006958099,0.0002933179,0.000002674054,0.00009462883,0.00001007374,0.00009274337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00639395,"threshold_uncertainty_score":0.3870694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01402815111001719,"score_gpt":0.236035043213702,"score_spread":0.2220068921036848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}