{"id":"W3187475154","doi":"10.1096/fj.202100395r","title":"Atypic SUMOylation of Nor1/NR4A3 regulates neural cell viability and redox sensitivity","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; SUMO protein; Cell biology; Transcription factor; Death-associated protein 6; Molecular biology; Nuclear protein; Biochemistry; Ubiquitin; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006090938,0.00007291971,0.0001225097,0.00002366556,0.0002684838,0.00006960452,0.0000668767,0.000031197,0.0001354845],"category_scores_gemma":[0.0002657851,0.00005049742,0.00006313922,0.0001282008,0.0001353572,0.0001312106,0.00006244736,0.0002446906,0.00000508082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001667578,"about_ca_system_score_gemma":0.00003105574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008390127,"about_ca_topic_score_gemma":0.00000472255,"domain_scores_codex":[0.9988277,0.0005057422,0.0001879136,0.0001441769,0.000193864,0.0001406333],"domain_scores_gemma":[0.9992687,0.0003189097,0.0001333223,0.0001501032,0.00006641489,0.00006252466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002993443,0.00002717724,0.002942482,0.000009077639,0.000001670531,0.0000254679,0.000295726,0.0002813422,0.9946775,0.00006447949,0.00004041454,0.001604715],"study_design_scores_gemma":[0.0001728744,0.00003323554,0.008697555,0.00001280187,0.00001164587,0.0003555412,0.0001240061,0.006291347,0.9833199,0.0008493225,0.00007452456,0.00005721553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998717,0.00007023953,0.0001007848,0.0004539121,0.0002002237,0.00004648311,0.000004517125,0.000009833014,0.0003970061],"genre_scores_gemma":[0.9994767,0.00003188938,0.00009566264,0.00008681132,0.00009199799,1.487737e-7,4.010841e-7,0.000007999693,0.0002083806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01135758,"threshold_uncertainty_score":0.2064988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01937105054468736,"score_gpt":0.2314600755572936,"score_spread":0.2120890250126062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}