{"id":"W3187608952","doi":"10.3390/nano11081984","title":"Targeting Intracellular Mycobacteria Using Nanosized Niosomes Loaded with Antibacterial Agents","year":2021,"lang":"en","type":"article","venue":"Nanomaterials","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"British Columbia Lung Association; Joint Programming Initiative on Antimicrobial Resistance","keywords":"Intracellular; Niosome; Cytotoxicity; Microbiology; Intracellular parasite; Macrophage; Secretion; Cytoplasm; Drug delivery; Antimicrobial; MTT assay; Mycobacterium; Biology; Chemistry; Cell; Cell biology; Vesicle; Bacteria; Membrane; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009592067,0.0002742718,0.0002224128,0.0001437297,0.0000993439,0.0002642348,0.0002065213,0.000374687,0.0003834173],"category_scores_gemma":[0.000108696,0.0001284473,0.0001945219,0.00006638069,0.0001858077,0.0002915807,0.0002429598,0.0002205746,0.0002682434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002629664,"about_ca_system_score_gemma":0.0001343991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002540006,"about_ca_topic_score_gemma":0.000446006,"domain_scores_codex":[0.9999274,0.000008387879,0.000007424732,0.00002154807,0.00001905937,0.0000162297],"domain_scores_gemma":[0.999939,0.000008014602,0.000020414,0.000006720134,0.00001580822,0.00001007644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003951641,0.00001651305,0.00008518062,0.00006679574,0.000003461646,0.00002806265,0.00000955413,0.0001041984,0.9983368,0.00008502754,0.00002809071,0.001196857],"study_design_scores_gemma":[0.00001320213,0.0002245412,0.0004964827,0.000008775546,0.00001358544,0.00008659979,0.00001148521,0.00120047,0.9954278,0.00002634322,0.002486068,0.000004666505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795689,0.003488364,0.01365213,0.0001483137,0.0000580919,0.0001011487,0.0001183211,0.0001478715,0.00271693],"genre_scores_gemma":[0.9827179,0.001290927,0.01356974,0.00008778649,0.00001499294,0.00007773106,0.0001509936,0.00002699221,0.002062902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003834173,"threshold_uncertainty_score":0.001907945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09338601543755823,"score_gpt":0.3976611931016965,"score_spread":0.3042751776641383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}