{"id":"W3187635066","doi":"10.3390/biom11081177","title":"The Effect of Oxygen and Micronutrient Composition of Cell Growth Media on Cancer Cell Bioenergetics and Mitochondrial Networks","year":2021,"lang":"en","type":"article","venue":"Biomolecules","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bioenergetics; Extracellular; Cell culture; Cancer cell; Glycolysis; Biology; Glutaminolysis; Mitochondrion; Metabolism; Lactate dehydrogenase; Cell; Cell biology; Biochemistry; Chemistry; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006779913,0.0001257718,0.0001676828,0.00001505724,0.00005641449,0.00001388918,0.00007226806,0.0001074646,0.000002102882],"category_scores_gemma":[0.00001648999,0.00009346374,0.00006375562,0.00005733055,0.0002042139,0.000001697704,0.00008139508,0.00004009536,1.21636e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000061208,"about_ca_system_score_gemma":0.00003274938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009577641,"about_ca_topic_score_gemma":0.00009998171,"domain_scores_codex":[0.999281,0.00009780539,0.0001636768,0.000221725,0.0000938295,0.0001419991],"domain_scores_gemma":[0.9995431,0.00004973276,0.0001005982,0.0001703932,0.00007899259,0.00005721631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002682571,0.00003384795,0.0001527802,0.0000621457,0.00002961974,7.614492e-7,0.00003464597,0.00001278943,0.9965546,0.00006047173,0.001137583,0.001652572],"study_design_scores_gemma":[0.001041325,0.000294115,0.0006048506,0.00002341688,0.00006927159,0.000003313577,0.00003244582,0.00003147832,0.9888162,0.000008819646,0.008976882,0.00009790622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9274611,0.07107005,0.0003074645,0.0000708724,0.0007736128,0.0001257749,0.00006691008,0.00000256165,0.0001216132],"genre_scores_gemma":[0.9656131,0.0334065,0.0002584319,0.00004872945,0.0005171965,0.00001367819,0.00008542532,0.00001426254,0.00004272257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03815191,"threshold_uncertainty_score":0.381134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003201508704003308,"score_gpt":0.2094027524111388,"score_spread":0.2062012437071355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}