{"id":"W3187635066","doi":"10.3390/biom11081177","title":"The Effect of Oxygen and Micronutrient Composition of Cell Growth Media on Cancer Cell Bioenergetics and Mitochondrial Networks","year":2021,"lang":"en","type":"article","venue":"Biomolecules","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bioenergetics; Extracellular; Cell culture; Cancer cell; Glycolysis; Biology; Glutaminolysis; Mitochondrion; Metabolism; Lactate dehydrogenase; Cell; Cell biology; Biochemistry; Chemistry; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001717703,0.000337253,0.0001834115,0.000176625,0.0002125847,0.0004267221,0.000187435,0.000183068,0.00100488],"category_scores_gemma":[0.0002100342,0.00009670546,0.0001555447,0.0002392932,0.0001985206,0.0002766676,0.0002442414,0.0002696704,0.0001404734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002862544,"about_ca_system_score_gemma":0.0002860435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00177728,"about_ca_topic_score_gemma":0.00275175,"domain_scores_codex":[0.9998049,0.00005037537,0.0000231203,0.00004576383,0.00004252571,0.00003333571],"domain_scores_gemma":[0.9998103,0.00006371053,0.00004353159,0.00001792639,0.00003312157,0.00003147062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000731491,0.0001048916,0.001832609,0.0001002975,0.00002114045,0.00009053366,0.00007224605,0.0002296673,0.9929591,0.0001328887,0.0001145953,0.003610393],"study_design_scores_gemma":[0.00001113824,0.0004333079,0.007564011,0.000008916421,0.00002131418,0.00006558066,0.00006843969,0.0004929531,0.9892965,0.00003648811,0.001994671,0.000006655539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918849,0.002257618,0.00168627,0.000134744,0.00005131687,0.0000477699,0.0009102854,0.00004065341,0.002986272],"genre_scores_gemma":[0.9917884,0.001624527,0.003733472,0.000137786,0.00001639203,0.00008140989,0.0009522942,0.00002351062,0.001642051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00177728,"threshold_uncertainty_score":0.0035339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003201508704003308,"score_gpt":0.2094027524111388,"score_spread":0.2062012437071355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}