{"id":"W3187753422","doi":"10.1016/j.jbc.2021.101046","title":"Actinobacillus utilizes a binding protein–dependent ABC transporter to acquire the active form of vitamin B6","year":2021,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Operon; Periplasmic space; ATP-binding cassette transporter; Biochemistry; Biology; Bacterial outer membrane; Escherichia coli; Chemistry; Transporter; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006633715,0.0003553958,0.000213064,0.0002254511,0.0002434646,0.0002947578,0.0001756734,0.000313603,0.0003891824],"category_scores_gemma":[0.0001182777,0.000132983,0.0002554812,0.0003052086,0.0001524673,0.0002222906,0.0002581142,0.0002747353,0.0004005981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002239897,"about_ca_system_score_gemma":0.0002376027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003517559,"about_ca_topic_score_gemma":0.001981945,"domain_scores_codex":[0.9999052,0.00001408785,0.000008203557,0.00001944859,0.00003174219,0.00002132879],"domain_scores_gemma":[0.9999512,0.000006162068,0.00001315132,0.000007051141,0.00001001231,0.00001239571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004642882,0.00002188562,0.001716594,0.00005691715,0.000006438646,0.0002080492,0.00002748465,0.0001182669,0.9953176,0.0001612107,0.00003821783,0.00228104],"study_design_scores_gemma":[0.00001758587,0.000268079,0.03453579,0.00002844493,0.00004977314,0.00210298,0.000257819,0.006571734,0.9475644,0.0002875092,0.008293079,0.0000228219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993174,0.0006662384,0.00444862,0.00009379751,0.00001124361,0.00001881795,0.0002280576,0.0001238059,0.001235474],"genre_scores_gemma":[0.9914361,0.0004793089,0.005960353,0.00003751678,0.000004103411,0.00001283845,0.0006177829,0.00001630347,0.001435793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003517559,"threshold_uncertainty_score":0.006994188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01804965190054589,"score_gpt":0.2586339788537631,"score_spread":0.2405843269532172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}