{"id":"W3187828028","doi":"10.1016/j.cbi.2021.109603","title":"Myrsinoic acid B from Myrsine coriacea reverses depressive-like behavior and brain oxidative stress in streptozotocin-diabetic rats","year":2021,"lang":"en","type":"article","venue":"Chemico-Biological Interactions","topic":"Silymarin and Mushroom Poisoning","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Physiotherapy Foundation of Canada; Hispanics in Philanthropy","keywords":"Oxidative stress; Streptozotocin; Behavioural despair test; Endocrinology; Internal medicine; Open field; Superoxide dismutase; Diabetes mellitus; Catalase; Chemistry; Hippocampus; Pharmacology; Medicine; Antidepressant","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006320151,0.0002518216,0.0004790656,0.00008411943,0.00009873317,0.00004410189,0.0000912119,0.0002177778,0.001717067],"category_scores_gemma":[0.0009691109,0.0002138086,0.0001039555,0.000279558,0.0001887162,0.0001450569,0.000172592,0.0006394127,0.00003046368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001597862,"about_ca_system_score_gemma":0.00009031387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001723275,"about_ca_topic_score_gemma":0.0001276794,"domain_scores_codex":[0.9984517,0.000100822,0.0003746649,0.00062372,0.0001167455,0.0003323395],"domain_scores_gemma":[0.9985223,0.0006592562,0.0001205492,0.000323757,0.0001683041,0.0002057651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001096933,0.0004813143,0.1403729,0.0000197362,0.0000617402,0.0002397269,0.0002871391,0.000001129858,0.8540642,0.0000178017,0.002423031,0.001921641],"study_design_scores_gemma":[0.001549056,0.0001290286,0.1740825,0.0005021079,0.0001326868,0.0001325562,0.002091206,0.00004132218,0.8185385,0.00006966417,0.002479277,0.0002521226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953477,0.0008640309,0.00003042697,0.001027342,0.0004959228,0.0003772565,0.00009915321,0.00008011072,0.00167799],"genre_scores_gemma":[0.9956868,0.0001106033,0.0007608867,0.0008951711,0.0002098158,0.0001492625,0.0006131638,0.00001844113,0.001555873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03552569,"threshold_uncertainty_score":0.9991955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03882586819832285,"score_gpt":0.3226546531807699,"score_spread":0.283828784982447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}