{"id":"W3188081715","doi":"10.3233/nre-210071","title":"Efficacy and safety of onabotulinumtoxinA with standardized occupational therapy for treatment of pediatric upper limb spasticity: Phase III placebo-controlled randomized trial","year":2021,"lang":"en","type":"article","venue":"Neurorehabilitation","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Holland Bloorview Kids Rehabilitation Hospital","funders":"Allergan","keywords":"Medicine; Modified Ashworth scale; Placebo; Spasticity; Randomized controlled trial; Physical therapy; Clinical endpoint; Population; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003671326,0.002014955,0.003860293,0.0005168265,0.0007050175,0.001557291,0.00147923,0.002701282,0.006558039],"category_scores_gemma":[0.00285876,0.000759857,0.002554182,0.000683388,0.001507598,0.001171915,0.0004961469,0.002828154,0.0009254991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001459026,"about_ca_system_score_gemma":0.002664967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001532208,"about_ca_topic_score_gemma":0.003046909,"domain_scores_codex":[0.9984529,0.0008073939,0.000129518,0.0002509248,0.0001699987,0.0001893451],"domain_scores_gemma":[0.9982429,0.0004138662,0.0006245393,0.0001564268,0.000128614,0.0004337244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9744772,0.008797175,0.0005966334,0.0007982984,0.001235622,0.00003597995,0.00004843021,0.0001676751,0.001913674,0.00006911579,0.0006209551,0.01123912],"study_design_scores_gemma":[0.9532249,0.04463469,0.0009765793,0.00003978478,0.000314859,0.00002257949,0.00001263826,0.0001368038,0.000245412,0.00005453801,0.0003304048,0.000006715103],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9666446,0.008385739,0.001433966,0.001001706,0.0006761501,0.01650672,0.002596047,0.000213848,0.002541119],"genre_scores_gemma":[0.9590458,0.00591669,0.003207212,0.00181641,0.0007312596,0.02429426,0.002136077,0.0000528804,0.00279936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006558039,"threshold_uncertainty_score":0.0219388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02283102573207892,"score_gpt":0.3225923012595911,"score_spread":0.2997612755275122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}