{"id":"W3188159150","doi":"10.1093/rheumatology/keab543","title":"Impact of filgotinib on sacroiliac joint magnetic resonance imaging structural lesions at 12 weeks in patients with active ankylosing spondylitis (TORTUGA trial)","year":2021,"lang":"en","type":"article","venue":"Lara D. Veeken","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Regeneron Pharmaceuticals; Celgene; Gilead Sciences; Sanofi; GlaxoSmithKline; Chugai Pharmaceutical; Galápagos; Pfizer; University of Alberta; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Ankylosing spondylitis; Medicine; Magnetic resonance imaging; Sacroiliac joint; Spondylitis; Radiology; Nuclear medicine; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000591679,0.0005620037,0.001043701,0.0001287578,0.0002581848,0.0006444993,0.0002968577,0.0005586743,0.001906782],"category_scores_gemma":[0.0007683079,0.0001672702,0.0006772862,0.0001250531,0.0003222478,0.0002788316,0.0001650207,0.0008088952,0.0001855322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000356503,"about_ca_system_score_gemma":0.0003513795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002288127,"about_ca_topic_score_gemma":0.008342911,"domain_scores_codex":[0.9998403,0.00007292265,0.000010164,0.00002475004,0.0000206572,0.00003133165],"domain_scores_gemma":[0.9997134,0.00005625537,0.00009559018,0.00001494579,0.00003013868,0.00008971761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8113959,0.004739381,0.02081413,0.00327056,0.004052438,0.0003433044,0.0003293605,0.001410919,0.01971592,0.0002774342,0.004774767,0.1288758],"study_design_scores_gemma":[0.4953674,0.289303,0.1964226,0.0004489694,0.00490681,0.001211719,0.0003407389,0.00201663,0.002349365,0.0002982999,0.007257075,0.00007743119],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909045,0.007083353,0.00005877794,0.000201157,0.00006682936,0.0001184967,0.0002246813,0.00003158172,0.001310542],"genre_scores_gemma":[0.9964485,0.001674213,0.0002113809,0.0002298909,0.00009819564,0.0001179896,0.0003962398,0.000002717551,0.0008208004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002288127,"threshold_uncertainty_score":0.006378829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0150925240153678,"score_gpt":0.2702386539046721,"score_spread":0.2551461298893042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}