{"id":"W3189112222","doi":"10.1002/cncr.33679","title":"Genetic risk assessment for hereditary renal cell carcinoma: Clinical consensus statement","year":2021,"lang":"en","type":"article","venue":"Cancer","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Center for Advancing Translational Sciences; National Cancer Institute","keywords":"Medicine; Genetic testing; Genetic counseling; Consensus conference; Family medicine; Delphi method; Risk assessment; Lynch syndrome; Cancer; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002733362,0.0002155561,0.0004579882,0.00003683735,0.00008809794,0.00001782876,0.00006231228,0.0001034252,0.0006175329],"category_scores_gemma":[0.0000528384,0.0001820114,0.0002964649,0.00009718216,0.00008475748,0.00001618009,0.00005611414,0.0002469905,0.00002497262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005378426,"about_ca_system_score_gemma":0.001472685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001772433,"about_ca_topic_score_gemma":0.00008805846,"domain_scores_codex":[0.9979651,0.0001459171,0.0006479934,0.0005526872,0.0003144596,0.0003738431],"domain_scores_gemma":[0.9983934,0.0002460916,0.0001909132,0.0004962919,0.0003636585,0.0003096729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007351841,0.001090047,0.8253013,0.0004949901,0.0005589382,0.003617723,0.0001326511,0.0003296539,0.006150668,0.00002343851,0.1339927,0.0275727],"study_design_scores_gemma":[0.008733067,0.001361873,0.9164277,0.0000716641,0.00124682,0.0001097194,0.0002147408,0.0009861374,0.02784798,0.0001375805,0.04259114,0.0002715849],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841419,0.009246932,0.0007491743,0.001302393,0.00102589,0.0008433122,0.000254518,0.00003263453,0.002403184],"genre_scores_gemma":[0.9691843,0.0006647904,0.02479163,0.00062031,0.001016228,0.0003582877,0.00009846301,0.00004487941,0.003221045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09140152,"threshold_uncertainty_score":0.7422208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05874805789207591,"score_gpt":0.3767577924033976,"score_spread":0.3180097345113216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}