{"id":"W3189195688","doi":"10.1161/hypertensionaha.121.16501","title":"Lowering Nighttime Blood Pressure With Bedtime Dosing of Antihypertensive Medications: Controversies in Hypertension - Con Side of the Argument","year":2021,"lang":"en","type":"article","venue":"Hypertension","topic":"Blood Pressure and Hypertension Studies","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Bedtime; Blood pressure; Medicine; Dosing; Argument (complex analysis); Chronotherapy (sleep phase); Ambulatory blood pressure; Internal medicine; Cardiology; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002361045,0.0003051087,0.001321255,0.0001672487,0.0001513096,0.00001102086,0.0001457427,0.0001916242,0.00004214699],"category_scores_gemma":[0.0005212921,0.0001857872,0.0002071276,0.0005470056,0.0003473568,0.0001002558,0.0002311988,0.0003366078,0.000004395965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000993954,"about_ca_system_score_gemma":0.0002533412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002174935,"about_ca_topic_score_gemma":0.00006179018,"domain_scores_codex":[0.9975587,0.0001210295,0.0006905718,0.0005151638,0.0007656206,0.0003489901],"domain_scores_gemma":[0.9967412,0.000533114,0.0003365855,0.0008390489,0.001443313,0.0001067788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005926362,0.001188683,0.0216129,0.0004055639,0.002169638,0.000680703,0.0006092092,0.00007822608,0.9686413,0.0001258534,0.003259578,0.0006357533],"study_design_scores_gemma":[0.01233161,0.0007002272,0.1346541,0.005382487,0.01506652,0.003590293,0.00298399,0.00097916,0.8141069,0.00007395911,0.009622347,0.0005084031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9524558,0.0381739,0.00001387914,0.006789447,0.0002706937,0.0006973394,0.00002139449,0.00003926596,0.001538294],"genre_scores_gemma":[0.994009,0.001048241,0.0008188057,0.003654666,0.00006734155,0.00001298037,0.00001550397,0.00003819639,0.0003352773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1545344,"threshold_uncertainty_score":0.7576184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01795772119302992,"score_gpt":0.228559586082633,"score_spread":0.2106018648896031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}