{"id":"W3189243995","doi":"10.3390/life11080791","title":"Skeletal Effects of Bone-Targeted TGFbeta Inhibition in a Mouse Model of Duchenne Muscular Dystrophy","year":2021,"lang":"en","type":"article","venue":"Life","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Shriners Hospitals for Children - Canada","funders":"Shriners Hospitals for Children","keywords":"Duchenne muscular dystrophy; Medicine; Context (archaeology); Osteoporosis; Muscular dystrophy; Internal medicine; Endocrinology; Femur; Skeletal muscle; Biology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005428111,0.00009074136,0.0001939107,0.00003619889,0.00001307375,0.000001613239,0.00003720242,0.0001388085,0.000007322674],"category_scores_gemma":[0.0001766027,0.00009474024,0.0001092935,0.00007861306,0.00006643396,0.000003301899,0.00006128824,0.00006358205,0.000001202581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003186928,"about_ca_system_score_gemma":0.00008072715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001972958,"about_ca_topic_score_gemma":0.00001662912,"domain_scores_codex":[0.9993238,0.00006901324,0.0002056006,0.0002044004,0.0000661458,0.0001309786],"domain_scores_gemma":[0.9995741,0.00001024768,0.00007585797,0.0002341174,0.00006295248,0.00004267532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008071728,0.0001911018,0.0002986615,0.0001862923,0.00003558029,0.00000408167,0.00004156928,0.002857047,0.9959422,0.0002044195,0.00008347256,0.00007487377],"study_design_scores_gemma":[0.001063851,0.0001447674,0.001741521,0.00001952376,0.00001370949,8.323766e-7,0.00003200233,0.0009898271,0.9955254,0.0003317202,0.00003988168,0.00009695017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978653,0.0008777487,0.0009442206,0.00004752308,0.00003497096,0.00009104336,0.00002059684,0.000004049222,0.0001145421],"genre_scores_gemma":[0.9990454,0.0001141917,0.0004049471,0.00015077,0.00002732539,0.00001292894,0.0001667027,0.00001007885,0.00006770912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00186722,"threshold_uncertainty_score":0.3863395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004845183406274947,"score_gpt":0.2079699575671445,"score_spread":0.2031247741608696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}