{"id":"W3189347835","doi":"10.1002/cbic.202100352","title":"Biosynthesis of the Fungal Organophosphonate Fosfonochlorin Involves an Iron(II) and 2‐(Oxo)glutarate Dependent Oxacyclase","year":2021,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Photosynthetic Processes and Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Austrian Science Fund","keywords":"Chemistry; Hydroxylation; Moiety; Stereochemistry; Phosphonate; Biosynthesis; Dioxygenase; Substrate (aquarium); Heme; Enzyme; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009524529,0.000452469,0.0001475548,0.0001309691,0.0001465683,0.0002648055,0.0001208579,0.0003070415,0.0003016269],"category_scores_gemma":[0.00012256,0.0001023321,0.0001788067,0.0001158363,0.000245471,0.0003018162,0.0002046641,0.0002528922,0.0001902259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005569769,"about_ca_system_score_gemma":0.0003038012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001366912,"about_ca_topic_score_gemma":0.001689729,"domain_scores_codex":[0.9999139,0.000009624842,0.000005684482,0.00002812285,0.0000246533,0.00001794193],"domain_scores_gemma":[0.9999149,0.0000132224,0.00002845297,0.00001045577,0.00001448856,0.00001834142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003978888,0.000006556309,0.0004133899,0.0000155837,0.000001764691,0.00004375901,0.00001215429,0.00005453792,0.9976727,0.0001266367,0.000008420845,0.001604527],"study_design_scores_gemma":[0.000003212652,0.00008629824,0.003345416,0.000002104073,0.00000482945,0.000272718,0.00002355715,0.000263483,0.9945931,0.00007035871,0.001330293,0.000004529935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896752,0.0005564371,0.007509965,0.0001067096,0.00001433115,0.00002847639,0.000281693,0.00005800985,0.001769258],"genre_scores_gemma":[0.9920379,0.0003133995,0.005758852,0.00002482794,0.000003214616,0.000009014624,0.0004011849,0.00001290437,0.001438695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001366912,"threshold_uncertainty_score":0.004041135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006772567140433553,"score_gpt":0.2052867283415298,"score_spread":0.1985141612010962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}