{"id":"W3189990959","doi":"10.1021/acsami.1c10618","title":"Uptake of Upconverting Nanoparticles by Breast Cancer Cells: Surface Coating versus the Protein Corona","year":2021,"lang":"en","type":"article","venue":"ACS Applied Materials & Interfaces","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de recherche du Québec – Nature et technologies; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Lietuvos Mokslo Taryba; Canada Foundation for Innovation","keywords":"Endocytosis; Biocompatibility; Materials science; Nanoparticle; Nanotechnology; Drug delivery; Biophysics; Nanomedicine; Cancer cell; Surface modification; Protein adsorption; Endocytic cycle; Phospholipid; Cell; Cancer; Chemistry; Biochemistry; Biology; Polymer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001502252,0.0003188252,0.0002429811,0.0001020488,0.00008773921,0.0002187537,0.0001574187,0.0002661217,0.0009287543],"category_scores_gemma":[0.0001950613,0.0001409688,0.0002002984,0.0001063914,0.0001467423,0.0002585262,0.0001433386,0.0003122018,0.0003581745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002532901,"about_ca_system_score_gemma":0.0001640756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001247102,"about_ca_topic_score_gemma":0.00139067,"domain_scores_codex":[0.9998866,0.00001397203,0.000006970696,0.00003666028,0.00002874002,0.00002711978],"domain_scores_gemma":[0.9999244,0.00002740976,0.00001265725,0.000009230407,0.00001805341,0.000008275267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003128672,0.000005284545,0.0000561948,0.00002177645,0.000002563245,0.00002040934,0.00001598164,0.00004446973,0.9986283,0.00002664353,0.00001639871,0.001130682],"study_design_scores_gemma":[0.000001316896,0.00004180654,0.0007942671,0.00000123018,0.000007056839,0.00005657089,0.00000669084,0.0004657197,0.998023,0.000005202628,0.000595107,0.000002088364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895727,0.001649701,0.005330054,0.00007230193,0.00002722329,0.00002616309,0.000158301,0.0001206355,0.003042771],"genre_scores_gemma":[0.9876602,0.00094898,0.005911288,0.00006159388,0.000008598548,0.0000300166,0.0003324296,0.00006116366,0.004985773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001247102,"threshold_uncertainty_score":0.003107011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01576626089113022,"score_gpt":0.2423483905189127,"score_spread":0.2265821296277825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}