{"id":"W3190000798","doi":"10.2139/ssrn.3866840","title":"DDX41 Is Required to Activate and Modulate cGAS-STING Activation","year":2021,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Sting; Cell biology; Chemistry; Biology; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002001415,0.0004697075,0.0003943566,0.0002444271,0.0004499174,0.0009404487,0.0003282837,0.0006548458,0.004938302],"category_scores_gemma":[0.000382081,0.0003048498,0.0003750142,0.0001761361,0.0003636979,0.0003477109,0.0005845875,0.0008224354,0.002248535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004531905,"about_ca_system_score_gemma":0.0002575598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002429322,"about_ca_topic_score_gemma":0.0003116674,"domain_scores_codex":[0.9995832,0.00007478239,0.00004361095,0.00008741813,0.00009469287,0.0001162694],"domain_scores_gemma":[0.999788,0.00005105842,0.00005367062,0.00005094237,0.00001810985,0.00003826415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001575031,0.00002520103,0.0001986614,0.00002065099,0.000004658762,0.0001517473,0.00001299006,0.00006811484,0.9980652,0.0001677933,0.00008506588,0.001042445],"study_design_scores_gemma":[0.00001748446,0.00006562555,0.005591396,0.000007394057,0.000006303553,0.0003497569,0.00004616955,0.0009831693,0.9899974,0.0001211837,0.002807376,0.000006820669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992916,0.001091399,0.001792067,0.0001959005,0.00009030932,0.00002441517,0.0004880994,0.0001639754,0.003237907],"genre_scores_gemma":[0.9943801,0.0002472943,0.0008637143,0.00006986069,0.00001393517,0.00002306087,0.0009367969,0.00004223314,0.003423056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004938302,"threshold_uncertainty_score":0.01652026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01112535691544441,"score_gpt":0.2506661964405982,"score_spread":0.2395408395251538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}