{"id":"W3190186455","doi":"10.1186/s13054-021-03698-z","title":"Association of cerebrospinal fluid protein biomarkers with outcomes in patients with traumatic and non-traumatic acute brain injury: systematic review of the literature","year":2021,"lang":"en","type":"review","venue":"Critical Care","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Traumatic brain injury; Biomarker; Glasgow Outcome Scale; Subarachnoid hemorrhage; Internal medicine; Cerebrospinal fluid; Bioinformatics; Intensive care medicine; Psychiatry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002497539,0.0003383414,0.001785229,0.00005677958,0.00003718127,0.00003400863,0.0002212527,0.0002887254,0.000005240478],"category_scores_gemma":[0.0008856229,0.0001780945,0.0002828763,0.0003417457,0.0001039088,0.000007765342,0.00008789183,0.0002041868,2.877296e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006055883,"about_ca_system_score_gemma":0.0001836792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003693654,"about_ca_topic_score_gemma":0.00001186865,"domain_scores_codex":[0.9979739,0.0003984402,0.000725312,0.0003359344,0.0003601623,0.0002062667],"domain_scores_gemma":[0.9985267,0.00006569517,0.0004019335,0.0005049748,0.0004450089,0.00005568214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00001372485,0.00008109758,0.0006494825,0.9973555,0.000405752,0.000002486536,0.00008396665,9.840695e-9,0.00002224095,0.00002702846,0.0000328172,0.001325865],"study_design_scores_gemma":[0.0004346893,0.0007744149,0.0006121117,0.9951727,0.002044812,0.000005900982,0.0001671057,2.309253e-7,0.0001433975,0.00000298732,0.0003510937,0.0002905725],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01040653,0.9857373,0.000009945479,0.0001162735,0.00002702196,0.003262862,0.0004068132,0.000002929192,0.00003038499],"genre_scores_gemma":[0.09382656,0.9022641,0.0007038292,0.0003668748,0.00004823232,0.001287341,0.001165036,0.0001354772,0.0002025306],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.08347312,"threshold_uncertainty_score":0.7262484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008316466921561608,"score_gpt":0.2951214794970375,"score_spread":0.2868050125754759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}