{"id":"W3190323073","doi":"10.1002/sctm.21-0161","title":"Process Parameter Development for the Scaled Generation of Stem Cell-Derived Pancreatic Endocrine Cells","year":2021,"lang":"en","type":"article","venue":"Stem Cells Translational Medicine","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Induced pluripotent stem cell; Stem cell; Progenitor cell; Diabetes mellitus; Medicine; Islet cell transplantation; Transplantation; Type 1 diabetes; Bioinformatics; Biology; Immunology; Internal medicine; Cell biology; Endocrinology; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002179953,0.0009945086,0.0005884041,0.0006991606,0.0004361335,0.00129854,0.0007328431,0.0006111154,0.002037224],"category_scores_gemma":[0.002510854,0.0003496209,0.0007416522,0.0009443437,0.0004317766,0.0007614535,0.0007410467,0.001397427,0.0008610135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000627128,"about_ca_system_score_gemma":0.001084126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007849173,"about_ca_topic_score_gemma":0.001818604,"domain_scores_codex":[0.9992167,0.00008915084,0.0001066962,0.0001225869,0.0004145261,0.00005033983],"domain_scores_gemma":[0.9991632,0.0002573082,0.0001570874,0.0001158723,0.0002657909,0.00004085871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000159069,0.0001712126,0.00130566,0.0008185036,0.00004233657,0.0002642407,0.000218978,0.02150745,0.9296482,0.002825987,0.0007504291,0.04228802],"study_design_scores_gemma":[0.00004599889,0.000694104,0.001998127,0.0001004418,0.0000879522,0.0001556117,0.0001033853,0.025072,0.9482625,0.002216597,0.02119826,0.00006497619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2735113,0.01002658,0.6986881,0.0008069961,0.0006660811,0.001523752,0.001961695,0.001960234,0.01085523],"genre_scores_gemma":[0.5433244,0.007270891,0.4437499,0.0002495983,0.00008379733,0.001207283,0.001693761,0.0004699061,0.001950485],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002179953,"threshold_uncertainty_score":0.01152879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04719069417852118,"score_gpt":0.2739573157734865,"score_spread":0.2267666215949653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}