{"id":"W3190598211","doi":"","title":"Systems and Synthetic Biology Approaches to Mechanobiology","year":2018,"lang":"en","type":"article","venue":"eScholarship (California Digital Library)","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Siebel Scholars Foundation; W. M. Keck Foundation; Division of Civil, Mechanical and Manufacturing Innovation; National Institutes of Health; National Science Foundation","keywords":"Stress fiber; Phosphorylation; Kinase; Cell biology; Biology; Crosstalk; Signal transduction; Mechanobiology; Neuroscience; Physics; Focal adhesion","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001278609,0.0008670994,0.0009877064,0.001115278,0.0006879744,0.001981696,0.001380614,0.001424011,0.007144825],"category_scores_gemma":[0.001687013,0.0005801815,0.001055633,0.0006566566,0.003863355,0.002190282,0.00238645,0.003632262,0.001902188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00172984,"about_ca_system_score_gemma":0.001318306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009122838,"about_ca_topic_score_gemma":0.0006226063,"domain_scores_codex":[0.9991504,0.0002479634,0.00005338027,0.0001936545,0.0002961567,0.00005854173],"domain_scores_gemma":[0.9992305,0.0003945233,0.00007150595,0.0001507102,0.0001086954,0.00004406992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00001498349,0.00003676385,0.0001480724,0.0005901897,0.00004303026,0.00008575981,0.0001293404,0.01042838,0.009182762,0.9485499,0.003247562,0.02754342],"study_design_scores_gemma":[0.0000315249,0.0001336473,0.0002368484,0.0002078137,0.00002643171,0.0001806464,0.00009643907,0.02798793,0.005377952,0.7946962,0.1709793,0.00004526992],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.009053463,0.04631761,0.8423882,0.01110861,0.002957852,0.0002875657,0.0005087945,0.0008877558,0.08649019],"genre_scores_gemma":[0.2751943,0.09535706,0.5759174,0.005586023,0.003455331,0.001987257,0.0009742741,0.0004610562,0.04106737],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.007144825,"threshold_uncertainty_score":0.02390188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03249744477038242,"score_gpt":0.2205285490970904,"score_spread":0.188031104326708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}