{"id":"W3190670641","doi":"10.1183/23120541.00447-2021","title":"An open-label study of the tolerability and potential efficacy of memantine for treating refractory chronic cough","year":2021,"lang":"en","type":"article","venue":"ERJ Open Research","topic":"Respiratory and Cough-Related Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"National Institute for Health and Care Research; McMaster University; Alfaisal University; Wellcome Trust; Medical Research Council; Wellcome","keywords":"Medicine; Tolerability; Refractory (planetary science); Chronic cough; Memantine; Anxiety; Depression (economics); Anesthesia; Internal medicine; NMDA receptor; Adverse effect; Receptor; Psychiatry; Asthma","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001830371,0.001514639,0.002803901,0.0006013446,0.0006765749,0.001005191,0.001215904,0.002097259,0.007837394],"category_scores_gemma":[0.001632173,0.0006010755,0.001593079,0.0004822056,0.001463701,0.001703949,0.0004030114,0.003787845,0.001474474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007682299,"about_ca_system_score_gemma":0.001060752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005763203,"about_ca_topic_score_gemma":0.001520591,"domain_scores_codex":[0.9991812,0.0003666826,0.00005966314,0.0001645276,0.000121942,0.0001058867],"domain_scores_gemma":[0.9985628,0.0004490156,0.0002648049,0.0001259112,0.0001039352,0.0004935606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7701863,0.1600441,0.0007053721,0.001259885,0.0007768616,0.0001707488,0.0001898958,0.0004690506,0.02246137,0.0002562398,0.001176339,0.04230385],"study_design_scores_gemma":[0.3485476,0.645196,0.002741575,0.00004876952,0.0002342324,0.00009147931,0.00005682496,0.000483275,0.001244599,0.0001231036,0.001201464,0.00003106938],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853793,0.004849434,0.000782569,0.0004278166,0.0005358984,0.004334176,0.001128279,0.0001037355,0.002458839],"genre_scores_gemma":[0.9806767,0.004003285,0.002109406,0.001009011,0.0008229095,0.005982627,0.001103975,0.00003447689,0.004257683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007837394,"threshold_uncertainty_score":0.02621865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1990713668379608,"score_gpt":0.5005104159326975,"score_spread":0.3014390490947367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}