{"id":"W3190953477","doi":"10.1371/journal.pgen.1009730","title":"A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene","year":2021,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Institute of Genetics; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Leukemia and Lymphoma Society of Canada","keywords":"Biology; Drosophila (subgenus); Oncogene; Drosophila melanogaster; Genetics; Evolutionary biology; Genetic screen; Computational biology; Cancer; Gene; Phenotype; Cell cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006482237,0.0005253942,0.0001619443,0.0005049673,0.000213698,0.0001742621,0.0002478545,0.0002437001,0.001054291],"category_scores_gemma":[0.00007452602,0.0001490475,0.0002352017,0.0002367736,0.0002486214,0.00008456409,0.0002478673,0.00032974,0.0002436874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003466658,"about_ca_system_score_gemma":0.0001879587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009244379,"about_ca_topic_score_gemma":0.003009635,"domain_scores_codex":[0.9999108,0.00001015556,0.000007518421,0.00002704777,0.00003188819,0.00001245992],"domain_scores_gemma":[0.9998978,0.00002868084,0.00003321424,0.000008791017,0.000005169126,0.00002624568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003103029,0.000009596623,0.0002792814,0.00001335648,0.000006244636,0.0001191686,0.000004701657,0.00005120989,0.9985971,0.0001015671,0.00001360168,0.0007731309],"study_design_scores_gemma":[0.00002024855,0.0002468131,0.01925321,0.000006466458,0.00005099941,0.001012988,0.00003750124,0.001502652,0.9748779,0.00009894878,0.002884333,0.000008019381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99317,0.0004104955,0.003399022,0.00006069076,0.00000888407,0.00004228445,0.001034302,0.000104704,0.001769709],"genre_scores_gemma":[0.990982,0.0004946029,0.005071983,0.0000398484,0.000003299199,0.00002616282,0.0009572695,0.00003100258,0.002393875],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001054291,"threshold_uncertainty_score":0.003526926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01667262841350186,"score_gpt":0.215547965296487,"score_spread":0.1988753368829851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}