{"id":"W3190957947","doi":"10.1177/13524585211035740","title":"Ocrelizumab treatment for relapsing-remitting multiple sclerosis after a suboptimal response to previous disease-modifying therapy: A nonrandomized controlled trial","year":2021,"lang":"en","type":"article","venue":"Multiple Sclerosis Journal","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Medicine; Ocrelizumab; Multiple sclerosis; Internal medicine; Clinical trial; Population; Relapsing remitting; Magnetic resonance imaging; Disease; Lesion; Oncology; Surgery; Radiology; Immunology; Rituximab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004155555,0.001048779,0.002525178,0.0003395898,0.0004331153,0.00100449,0.000676555,0.001655471,0.002793149],"category_scores_gemma":[0.003652843,0.0004174238,0.002244888,0.0004191388,0.0009465349,0.0006181125,0.0003285705,0.001363378,0.0004573876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006208633,"about_ca_system_score_gemma":0.001065815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006389871,"about_ca_topic_score_gemma":0.001172679,"domain_scores_codex":[0.9982181,0.001174877,0.0001442685,0.0002168244,0.0001150188,0.0001308469],"domain_scores_gemma":[0.9979677,0.0007281611,0.0006315751,0.0002275458,0.0001818924,0.000263107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9787764,0.003842926,0.001602072,0.0009429722,0.002311334,0.00004876222,0.00004263248,0.0001754833,0.001194467,0.00008058783,0.0003613906,0.01062109],"study_design_scores_gemma":[0.9540856,0.04168648,0.00233372,0.00005630076,0.0008850818,0.00004463222,0.00001220656,0.0002601881,0.0001777516,0.00007661812,0.0003729599,0.000008431671],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983134,0.01017167,0.000622197,0.0004769331,0.0004350691,0.003630839,0.0005025977,0.000060069,0.0009666847],"genre_scores_gemma":[0.9901482,0.003501696,0.001034152,0.0006162357,0.0004440061,0.003073215,0.0003994464,0.00001058674,0.0007722902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004155555,"threshold_uncertainty_score":0.02197695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1405478466227287,"score_gpt":0.3381254336079222,"score_spread":0.1975775869851935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}