{"id":"W3191008658","doi":"10.1093/cvr/cvab262","title":"Using multimarker screening to identify biomarkers associated with cardiovascular death in patients with atrial fibrillation","year":2021,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Population Health Research Institute","funders":"Duke Clinical Research Institute; Science for Life Laboratory; Uppsala Universitet; Stiftelsen för Strategisk Forskning; Hjärt-Lungfonden; Pfizer","keywords":"Medicine; Internal medicine; Hazard ratio; Cohort; Atrial fibrillation; GDF15; Biomarker; Proportional hazards model; Natriuretic peptide; Gastroenterology; Cardiology; Endocrinology; Oncology; Heart failure; Confidence interval; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00225265,0.0006112788,0.0005165652,0.001066563,0.0002845722,0.0007362419,0.0003735349,0.0006710674,0.001065498],"category_scores_gemma":[0.004345446,0.000239878,0.0005929159,0.0005765356,0.0001885091,0.0005494627,0.0004813714,0.0006479658,0.0002795844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002405518,"about_ca_system_score_gemma":0.0002956334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008679595,"about_ca_topic_score_gemma":0.001360784,"domain_scores_codex":[0.9988641,0.0005119931,0.00009102464,0.0002451822,0.0001810567,0.0001067102],"domain_scores_gemma":[0.9980354,0.0007479855,0.0006835019,0.0001798623,0.0001593144,0.0001940253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003673253,0.00008137686,0.9938766,0.00001256863,0.0001396883,0.00002787362,0.00002550291,0.0001316691,0.0004558372,0.00002027344,0.0001168342,0.004744458],"study_design_scores_gemma":[0.0001240512,0.001021,0.992918,0.00001576132,0.0001806313,0.0004546676,0.00005236292,0.003688024,0.0009341183,0.0001488841,0.0004441041,0.00001849419],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974491,0.0006166579,0.001004877,0.0001335623,0.00002435785,0.00003765459,0.0003487295,0.0000246443,0.0003604028],"genre_scores_gemma":[0.9980713,0.0001149696,0.001173612,0.00006209043,0.00003783232,0.0000391065,0.0002867163,0.000002058304,0.0002123301],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00225265,"threshold_uncertainty_score":0.0119133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0839178014585655,"score_gpt":0.3291791254385995,"score_spread":0.2452613239800339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}