{"id":"W3191008658","doi":"10.1093/cvr/cvab262","title":"Using multimarker screening to identify biomarkers associated with cardiovascular death in patients with atrial fibrillation","year":2021,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Population Health Research Institute","funders":"Duke Clinical Research Institute; Science for Life Laboratory; Uppsala Universitet; Stiftelsen för Strategisk Forskning; Hjärt-Lungfonden; Pfizer","keywords":"Medicine; Internal medicine; Hazard ratio; Cohort; Atrial fibrillation; GDF15; Biomarker; Proportional hazards model; Natriuretic peptide; Gastroenterology; Cardiology; Endocrinology; Oncology; Heart failure; Confidence interval; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00420312,0.0003215914,0.0008996946,0.0005594805,0.000521744,0.0001055934,0.0002672971,0.0003879863,0.00004198159],"category_scores_gemma":[0.001482986,0.0002807994,0.0009990468,0.001999904,0.0002042833,0.0002454029,0.0002914157,0.0006461599,0.00008082099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004073372,"about_ca_system_score_gemma":0.0004536844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008335922,"about_ca_topic_score_gemma":0.0001094034,"domain_scores_codex":[0.9939129,0.002761257,0.0003763048,0.0009949522,0.0008418412,0.001112782],"domain_scores_gemma":[0.9969177,0.0002533048,0.00005718446,0.001181938,0.001486721,0.0001032118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003325156,0.0001630664,0.8526146,0.0001381474,0.05377115,0.0007978434,0.0009419557,0.05019325,0.005917713,0.00002608139,0.000330709,0.03178033],"study_design_scores_gemma":[0.01535239,0.0003809998,0.9411411,0.000633834,0.000893913,0.00007471922,0.0004745258,0.0001637444,0.006277773,0.00001010103,0.03380428,0.0007926211],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850549,0.008163569,0.004605623,0.00001131661,0.0002600377,0.001077551,0.0002604249,0.0000610293,0.0005055614],"genre_scores_gemma":[0.9980876,0.00008062326,0.0009558276,0.00001126403,0.0001208994,0.00001605253,0.000525709,0.00007831477,0.0001237446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08852649,"threshold_uncertainty_score":0.9999644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0839178014585655,"score_gpt":0.3291791254385995,"score_spread":0.2452613239800339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}