{"id":"W3191051423","doi":"10.20944/preprints202108.0218.v1","title":"Nanoparticles for Cancer Therapy: Current Progress and Challenges","year":2021,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"Cancer; Cancer treatment; Medicine; Cancer therapy; Nanotechnology; Drug delivery; Immunotherapy; Radiation therapy; Materials science; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003965286,0.0008898523,0.001400199,0.001343357,0.0007867601,0.003206267,0.001206362,0.003278424,0.0061715],"category_scores_gemma":[0.002672028,0.0004612843,0.000724486,0.001274793,0.00157737,0.004489833,0.001880484,0.003729122,0.004578832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001148574,"about_ca_system_score_gemma":0.002187018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008308454,"about_ca_topic_score_gemma":0.0009041076,"domain_scores_codex":[0.9988055,0.0003204815,0.00008535563,0.0001950078,0.0004795663,0.0001140386],"domain_scores_gemma":[0.9982386,0.0008704635,0.000114055,0.00009005388,0.0005363136,0.0001505986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001452956,0.0001762664,0.0003237511,0.009780863,0.00005089113,0.0002118214,0.0002426355,0.001482719,0.007950125,0.04802538,0.05606912,0.8755412],"study_design_scores_gemma":[0.00002048145,0.0002194806,0.0002497419,0.002320776,0.00004250065,0.0006652388,0.0001804428,0.0007926734,0.003343302,0.02888334,0.9632421,0.0000399184],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004599434,0.9857702,0.002840038,0.005913724,0.0008681451,0.00001848279,0.00004289001,0.00006529861,0.004021205],"genre_scores_gemma":[0.004791996,0.9866289,0.003185375,0.001805249,0.001484011,0.00004609925,0.00009520166,0.00003121011,0.001931999],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0061715,"threshold_uncertainty_score":0.0209707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2026197208402914,"score_gpt":0.3739194859972172,"score_spread":0.1712997651569258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}