{"id":"W3191181461","doi":"10.21203/rs.3.rs-743701/v1","title":"CD73 Controls Ocular Adenosine Levels and Protects Retina from Light-Induced Phototoxicity","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Biocenter Finland; Turun Yliopisto; Université Laval","keywords":"Phototoxicity; Retina; Adenosine; Ophthalmology; Optometry; Chemistry; Medicine; Neuroscience; Biology; Biochemistry; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001062425,0.0002357567,0.0002280898,0.000376196,0.0003354182,0.0008947674,0.0002292524,0.0003763027,0.003406873],"category_scores_gemma":[0.000192798,0.0001440191,0.0001469242,0.0002361302,0.0003741297,0.0003521832,0.0002248484,0.0006017519,0.0005362634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005699413,"about_ca_system_score_gemma":0.0003477522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001232989,"about_ca_topic_score_gemma":0.001852272,"domain_scores_codex":[0.999864,0.000008351319,0.000004629434,0.0000281807,0.00003170357,0.00006316776],"domain_scores_gemma":[0.9999068,0.00001290093,0.00002607273,0.00001282622,0.00001180117,0.00002962395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004102956,0.00004513938,0.0002876677,0.00002525501,0.000004788943,0.0001278727,0.00001398229,0.00005191752,0.9920524,0.0009303605,0.0002596255,0.005790744],"study_design_scores_gemma":[0.00003977495,0.0001180708,0.006500585,0.000009328234,0.00002168373,0.0002578846,0.00007142312,0.001151259,0.9868685,0.0007606001,0.004193216,0.000007693228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866729,0.003042582,0.003261076,0.0003869919,0.00011685,0.0000152352,0.0002865946,0.0002105616,0.00600729],"genre_scores_gemma":[0.9909753,0.0008981884,0.001089793,0.00005875663,0.00002938172,0.00001163118,0.0001931742,0.00007270998,0.006671076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003406873,"threshold_uncertainty_score":0.01139718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05810200042132819,"score_gpt":0.3570908523850934,"score_spread":0.2989888519637652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}