{"id":"W3191249226","doi":"10.4049/jimmunol.2100311","title":"Critical Roles of Phosphoinositide 3-Kinase δ in the Humoral Immune Response to <i>Trypanosoma congolense</i> Infection","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Science Centre for Human and Animal Health; Canadian Food Inspection Agency; University of Manitoba","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Research Manitoba","keywords":"Trypanosoma; Immune system; Biology; Phosphoinositide 3-kinase; Virology; Immunology; Cell biology; Signal transduction; PI3K/AKT/mTOR pathway","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001252769,0.0003188909,0.000139336,0.0002239374,0.00013264,0.0002653234,0.0001490698,0.0002810749,0.0009624886],"category_scores_gemma":[0.00008559068,0.0001121022,0.0001735822,0.00007023732,0.0002874334,0.000155726,0.0001606951,0.0005755493,0.0002576991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003139491,"about_ca_system_score_gemma":0.0001784705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004802224,"about_ca_topic_score_gemma":0.0005807425,"domain_scores_codex":[0.9998916,0.0000205687,0.00001306995,0.00001792353,0.00002430251,0.00003239736],"domain_scores_gemma":[0.9999028,0.00000865028,0.00003453357,0.000006856934,0.0000102243,0.00003682353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000360618,0.00002636353,0.0004456186,0.00003342581,0.000002974386,0.00006212615,0.000008470006,0.00004119412,0.9980438,0.00007691394,0.00002785128,0.0008705888],"study_design_scores_gemma":[0.00005384808,0.0007415747,0.02217543,0.0000179768,0.00001855526,0.0005628015,0.00007636653,0.0006632726,0.9741457,0.0001203469,0.001418251,0.000005818217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949811,0.001918597,0.0009590203,0.000180865,0.00002756162,0.00003485378,0.0003865222,0.00007916913,0.001432368],"genre_scores_gemma":[0.9977869,0.0005167719,0.00058745,0.00006652996,0.000006218173,0.0000232712,0.0001783297,0.000007091109,0.0008275094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009624886,"threshold_uncertainty_score":0.003219843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01903188778438638,"score_gpt":0.3260158035126559,"score_spread":0.3069839157282695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}