{"id":"W3191748276","doi":"10.1093/humrep/deab130.207","title":"P–208 Oleic acid rescues altered autophagy induced by palmitic acid during mouse preimplantation development","year":2021,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"","keywords":"Autophagy; Palmitic acid; Blastocyst; Biology; Oleic acid; Andrology; Embryogenesis; Lipid droplet; Fatty acid; Embryo; Reproductive technology; Cell biology; Biochemistry; Apoptosis; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001774719,0.0002053826,0.0002652071,0.0001155665,0.0003279777,0.00004363451,0.00006719534,0.0001073261,0.0003019123],"category_scores_gemma":[0.00007691543,0.0002104504,0.00007641382,0.0001885041,0.00003419079,0.0001597563,0.00003713557,0.0002104868,0.000085028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001773011,"about_ca_system_score_gemma":0.0001463037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001059473,"about_ca_topic_score_gemma":0.000007920758,"domain_scores_codex":[0.9981108,0.00008910564,0.0004118528,0.0007632358,0.0003396771,0.0002853234],"domain_scores_gemma":[0.9988604,0.000005897936,0.0001339999,0.0007040633,0.0001668166,0.0001288481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001417031,0.0002685667,0.0004161501,0.0001613489,0.0001385997,0.00006463496,0.001090533,0.000002467903,0.9898204,0.00003935511,0.0004043959,0.00745187],"study_design_scores_gemma":[0.001354114,0.00008809577,0.0873353,0.00008192749,0.00006898425,0.0002181234,0.0001798727,0.000003939097,0.9095566,0.0001580453,0.0007634907,0.0001914865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996907,0.001448527,0.0000665929,0.0001953214,0.000387655,0.0003645907,0.000004914826,0.0002884562,0.000336918],"genre_scores_gemma":[0.9931626,0.00009900249,0.000402146,0.0001271956,0.0007168477,0.00008448196,0.0005448326,0.00004477275,0.00481814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08691915,"threshold_uncertainty_score":0.8581917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03022236783914519,"score_gpt":0.2973798170703624,"score_spread":0.2671574492312172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}