{"id":"W3192034877","doi":"10.7554/elife.64557.sa2","title":"Author response: Galectin-9 regulates the threshold of B cell activation and autoimmunity","year":2021,"lang":"en","type":"peer-review","venue":"","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Autoimmunity; B cell; Biology; Cell biology; Population; Regulatory B cells; Antigen; breakpoint cluster region; Immunology; Galectin; Naive B cell; B-cell receptor; Autoantibody; Peripheral tolerance; Antibody; Antigen-presenting cell; T cell; Immune system; Receptor; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001759291,0.001039844,0.0007004551,0.0009740897,0.0006757025,0.002464937,0.001334543,0.002481206,0.4136406],"category_scores_gemma":[0.005640191,0.0004228276,0.0006815153,0.0008118176,0.0005613816,0.00140514,0.001732476,0.001598577,0.1615107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001524705,"about_ca_system_score_gemma":0.00143513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004802711,"about_ca_topic_score_gemma":0.0005944624,"domain_scores_codex":[0.9971542,0.0005767921,0.0002586559,0.0005340586,0.001161788,0.0003143757],"domain_scores_gemma":[0.9961711,0.0007403941,0.0003756777,0.0002752182,0.001673713,0.0007639484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001279226,0.0001047935,0.001982934,0.001194899,0.00006508403,0.0002429072,0.00008052548,0.0007196139,0.01981606,0.003685964,0.8940279,0.0768001],"study_design_scores_gemma":[0.0003575908,0.0001953234,0.003274991,0.0002539653,0.00003466783,0.0004045498,0.0001991876,0.001064786,0.0263683,0.002795485,0.9649868,0.00006436466],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.03796122,0.01158158,0.04102594,0.159742,0.2507641,0.00268663,0.1060942,0.01654937,0.3735948],"genre_scores_gemma":[0.1462917,0.008684997,0.02012806,0.02350331,0.02002968,0.001463787,0.05295691,0.002980206,0.7239614],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.4136406,"threshold_uncertainty_score":0.8363705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03398662221274835,"score_gpt":0.3007507276089173,"score_spread":0.266764105396169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}