{"id":"W3192211563","doi":"10.1002/lt.26264","title":"Regorafenib Efficacy After Sorafenib in Patients With Recurrent Hepatocellular Carcinoma After Liver Transplantation: A Retrospective Study","year":2021,"lang":"en","type":"article","venue":"Liver Transplantation","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Toronto General Hospital; University of Toronto; University Health Network","funders":"Instituto de Salud Carlos III; Societat Catalana de Digestologia; Ministero della Salute; Generalitat de Catalunya; Fundación Científica Asociación Española Contra el Cáncer","keywords":"Regorafenib; Sorafenib; Medicine; Hepatocellular carcinoma; Discontinuation; Internal medicine; Hazard ratio; Liver transplantation; Retrospective cohort study; Adverse effect; Clinical endpoint; Surgery; Gastroenterology; Oncology; Transplantation; Confidence interval; Randomized controlled trial; Colorectal cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001104743,0.0002435817,0.0005941415,0.0005631206,0.0003464788,0.0005755649,0.0002677681,0.0003558356,0.0007644963],"category_scores_gemma":[0.001985617,0.0002147089,0.0009969163,0.0008716807,0.000318305,0.0003419676,0.0003160236,0.0003480602,0.0001489914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003650278,"about_ca_system_score_gemma":0.0003448811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001365208,"about_ca_topic_score_gemma":0.001303199,"domain_scores_codex":[0.9991094,0.0002197448,0.0001432821,0.0002617396,0.0001599462,0.0001058113],"domain_scores_gemma":[0.9977234,0.0003518752,0.001323863,0.000217476,0.0001638876,0.0002194982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007229499,0.00003907402,0.9963697,0.00002732185,0.0001668745,0.0002658815,0.00005454018,0.0000365687,0.0002625485,0.00001117967,0.00003520845,0.00200816],"study_design_scores_gemma":[0.00006650737,0.0009941114,0.9956054,0.00001182256,0.0002502307,0.002038015,0.000158102,0.0002102625,0.0001949336,0.00002221508,0.0004390366,0.000009344905],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989286,0.0007513228,0.00006570628,0.00001186202,0.00000339539,0.000008692436,0.00009435376,0.000001782272,0.0001342383],"genre_scores_gemma":[0.9996258,0.0001414576,0.00002419069,0.00001405185,0.000009670071,0.000005401848,0.0001538671,0.000001048769,0.00002450242],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001365208,"threshold_uncertainty_score":0.005842507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01938592659906107,"score_gpt":0.2193110175809026,"score_spread":0.1999250909818416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}