{"id":"W3192211563","doi":"10.1002/lt.26264","title":"Regorafenib Efficacy After Sorafenib in Patients With Recurrent Hepatocellular Carcinoma After Liver Transplantation: A Retrospective Study","year":2021,"lang":"en","type":"article","venue":"Liver Transplantation","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Toronto General Hospital; University of Toronto; University Health Network","funders":"Instituto de Salud Carlos III; Societat Catalana de Digestologia; Ministero della Salute; Generalitat de Catalunya; Fundación Científica Asociación Española Contra el Cáncer","keywords":"Regorafenib; Sorafenib; Medicine; Hepatocellular carcinoma; Discontinuation; Internal medicine; Hazard ratio; Liver transplantation; Retrospective cohort study; Adverse effect; Clinical endpoint; Surgery; Gastroenterology; Oncology; Transplantation; Confidence interval; Randomized controlled trial; Colorectal cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001447836,0.0004430505,0.0005339991,0.000262253,0.00008681381,0.00005557966,0.000079084,0.0001670373,0.0005042596],"category_scores_gemma":[0.000007052213,0.0003898292,0.0001816451,0.000621575,0.00006326467,0.0003330349,0.00001109681,0.0003492487,0.00007968579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002281287,"about_ca_system_score_gemma":0.0001444215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001708942,"about_ca_topic_score_gemma":0.0005714438,"domain_scores_codex":[0.9972157,0.0002846572,0.0004983025,0.0008409675,0.0007234753,0.000436932],"domain_scores_gemma":[0.9989402,0.00005470041,0.0001007102,0.0003930076,0.0003161618,0.0001951721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01273606,0.003072756,0.9342701,0.0005962293,0.0001748653,0.03543321,0.01278267,0.000001332609,0.00003304833,0.00001144379,0.000005212346,0.0008830805],"study_design_scores_gemma":[0.01703239,0.001924738,0.9763282,0.0004003589,0.001706607,0.0001547978,0.0001947705,0.0002777924,0.001521955,0.000007349889,0.00002522487,0.0004258187],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954806,0.001110551,0.0003006989,0.00006958106,0.0001251591,0.002398076,0.0001676385,0.00007374353,0.0002739314],"genre_scores_gemma":[0.9965445,0.0006369206,0.0006204995,0.00009046838,0.00008150595,0.0004950513,0.001335064,0.00006350171,0.0001325315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0420581,"threshold_uncertainty_score":0.9998553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01938592659906107,"score_gpt":0.2193110175809026,"score_spread":0.1999250909818416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}