{"id":"W3192433570","doi":"10.1002/chem.202102186","title":"Copper‐Promoted N‐Arylation of the Imidazole Side Chain of Protected Histidine by Using Triarylbismuth Reagents","year":2021,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Boehringer Ingelheim","keywords":"Imidazole; Histidine; Chemistry; Reagent; Dichloromethane; Side chain; Copper; Aryl; Medicinal chemistry; Combinatorial chemistry; Polymer chemistry; Organic chemistry; Solvent","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003701399,0.0001370693,0.000213143,0.00001075835,0.00009173366,0.00001721507,0.000247208,0.00006094257,0.0001077127],"category_scores_gemma":[0.0005004911,0.000106536,0.0002505536,0.0001788169,0.00008651215,0.000003600119,0.000138684,0.0001794552,6.200738e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002495124,"about_ca_system_score_gemma":0.0000956591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003302027,"about_ca_topic_score_gemma":2.401293e-7,"domain_scores_codex":[0.9987414,0.0002052064,0.0004843618,0.0002140574,0.0001992607,0.0001556562],"domain_scores_gemma":[0.9988903,0.00001183651,0.0004714363,0.0003245201,0.0002144186,0.00008751974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004504958,0.0000990718,0.0004119855,0.00004443998,0.0001038722,0.00000977812,0.00001817067,0.00005479963,0.9971446,1.317885e-7,0.0005964938,0.001471626],"study_design_scores_gemma":[0.0005107117,0.00001610813,0.0004674321,0.0001234433,0.00008157998,0.0001090286,0.0000422493,0.0006569144,0.9966614,0.000004039669,0.001213778,0.0001133799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980154,0.0006264189,0.0004432441,0.0001223051,0.00002958153,0.00005116083,0.00003701109,0.000003568584,0.0006713262],"genre_scores_gemma":[0.9988471,0.00007983491,0.0003553893,0.00002232285,0.0001680215,6.335286e-7,0.00006155881,0.00002392731,0.0004412161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001358246,"threshold_uncertainty_score":0.4344413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01324648634370823,"score_gpt":0.2188088389661733,"score_spread":0.205562352622465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}